Secondary metabolites profoundly affect microbial physiology, metabolism and stress
responses. Increasing evidence suggests that these molecules can modulate microbial …

The significance of polymicrobial infections is increasingly being recognized especially in a
biofilm context wherein multiple bacterial species—including both potential pathogens and …

The functional spectrum of a secretion system is defined by its substrates. Here we analyzed
the secretomes of Pseudomonas aeruginosa mutants altered in regulation of the Hcp …

The airways of patients with cystic fibrosis are colonized with diverse bacterial communities
that change dynamically during pediatric years and early adulthood. Staphylococcus aureus …

Since quinine was first isolated, animals, plants and microorganisms producing a wide
variety of quinolone compounds have been discovered, several of which possess …

Cytochrome bd is a respiratory quinol: O2 oxidoreductase found in many prokaryotes,
including a number of pathogens. The main bioenergetic function of the enzyme is the …

Pathogens that infect the gastrointestinal and respiratory tracts are subjected to intense
pressure due to the environmental conditions of the surroundings. This pressure has led to …

The airways of cystic fibrosis (CF) patients have thick mucus, which fosters chronic,
polymicrobial infections. Pseudomonas aeruginosa and Staphylococcus aureus are two of …

A hallmark feature of several pathogenic microbes is the distinctive color of their colonies
when propagated in the clinical laboratory. Such pigmentation comes in a variety of hues …

Cystic fibrosis (CF) is an autosomal recessive genetic disorder that is characterized by
recurrent and chronic infections of the lung predominantly by the opportunistic pathogens …