Background: Research on predictors of working memory training responsiveness, which
could help tailor cognitive interventions individually, is a timely topic in healthy aging …

Importance Better understanding is needed of the degree to which individuals tolerate
Alzheimer disease (AD)–like pathological tau with respect to brain structure (brain …

Alzheimer's disease (AD) manifests with progressive memory loss and spatial disorientation.
Neuropathological studies suggest early AD pathology in the entorhinal cortex (EC) of …

The recent development of several tau positron emission tomography (PET) tracers
represents a major milestone for the Alzheimer's disease (AD) field. These tau PET tracers …

Importance While amyloidosis is an early event in the Alzheimer disease (AD) biomarker
cascade, a complex interplay among the apolipoprotein E (APOE) ɛ4 allele, educational …

Mechanisms of resilience against tau pathology in individuals across the Alzheimer's
disease spectrum are insufficiently understood. Longitudinal data are necessary to reveal …

Alzheimer's disease is defined by the presence of β-amyloid plaques and neurofibrillary tau
tangles potentially preceding clinical symptoms by many years. Previously only detectable …

Objectives The purpose of this study was to explore whether psychological resilience can
influence changes in cognitive function in older adults and provide clues and rationale for …

Background Alzheimer's disease (AD) is a complex disease that shares clinical features with
other dementias. It is important to establish a specific and reliable diagnosis. Nowadays, AD …

Abstract Purpose [18 F] FDG-PET and [11 C] PIB-PET are validated as neurodegeneration
and amyloid biomarkers of Alzheimer's disease (AD). We used a PET staging system based …