Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update

P Morales, L Hernandez-Folgado, P Goya… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Modulation of the CB2 receptor is an interesting approach for pain and
inflammation, arthritis, addictions, neuroprotection, and cancer, among other possible …

Dose‐dependent cannabidiol‐induced elevation of intracellular calcium and apoptosis in human articular chondrocytes

M Winklmayr, M Gaisberger, M Kittl… - Journal of …, 2019 - Wiley Online Library
Cannabidiol (CBD) is the most abundant non‐psychoactive compound of Cannabis sativa
extracts. Cannabinoids have been shown to exhibit anti‐inflammatory, analgesic …

OP0325 safety and efficacy of lenabasum in an open-label extension of a phase 2 study in diffuse cutaneous systemic sclerosis subjects (DCSSC)

R Spiera, L Hummers, L Chung, T Frech… - Annals of the Rheumatic …, 2019 - Elsevier
Background Lenabasum is a synthetic, non-immunosuppressive, selective cannabinoid
receptor type 2 agonist that activates resolution of innate immune responses and limits …

OP0324 CANNABIDIOL ELEVATES INTRACELLULAR CALCIUM AND INDUCES APOPTOSIS IN HUMAN ARTICULAR CHONDROCYTES

M Gaisberger, J Fuchs, M Kittll, M Ritter, M Jakab - 2019 - ard.bmj.com
Background Osteoarthritis (OA) is a major public health problem among the increasing aged
and obese population, therefore development and investigation of new therapeutics is a …