Azines, such as pyridines, quinolines, pyrimidines, and pyridazines, are widespread
components of pharmaceuticals. Their occurrence derives from a suite of physiochemical …

Redox processes are at the heart of synthetic methods that rely on either electrochemistry or
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …

The development of late-stage functionalization (LSF) methodologies, particularly C–H
functionalization, has revolutionized the field of organic synthesis. Over the past decade …

Organosulfur compounds have long played a vital role in organic chemistry and in the
development of novel chemical structures and architectures. Prominent among these …

The electronic properties and relatively small size of fluorine endow it with considerable
versatility as a bioisostere and it has found application as a substitute for lone pairs of …

Reactions that involve the addition of carbon‐centered radicals to basic heteroarenes,
followed by formal hydrogen atom loss, have become widely known as Minisci‐type …

This Perspective illustrates the defining characteristics of free radical chemistry, beginning
with its rich and storied history. Studies from our laboratory are discussed along with recent …

While preparative electrolysis of organic molecules has been an active area of research
over the past century, modern synthetic chemists have generally been reluctant to adopt this …

Herein, we report a method for C3-selective C–H tri-and difluoromethylthiolation of
pyridines. The method relies on borane-catalyzed pyridine hydroboration for generation of …

Azines, which are six-membered aromatic compounds containing one or more nitrogen
atoms, serve as ubiquitous structural cores of aromatic species with important applications in …