Immunomodulatory properties of human breast milk: microRNA contents and potential epigenetic effects

MMM Hatmal, MAI Al-Hatamleh, AN Olaimat, W Alshaer… - Biomedicines, 2022 - mdpi.com
Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …

[HTML][HTML] Epigenetic modification impacting brain functions: Effects of physical activity, micronutrients, caffeine, toxins, and addictive substances

R Mallick, AK Duttaroy - Neurochemistry International, 2023 - Elsevier
Abstract Changes in gene expression are involved in many brain functions. Epigenetic
processes modulate gene expression by histone modification and DNA methylation or RNA …

Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease

Z Wang, S Zhu, Y Jia, Y Wang, N Kubota, N Fujiwara… - Cell, 2023 - cell.com
Somatic mutations in nonmalignant tissues accumulate with age and injury, but whether
these mutations are adaptive on the cellular or organismal levels is unclear. To interrogate …

The functional role of micro RNA s in alcoholic liver injury

K McDaniel, L Herrera, T Zhou… - Journal of cellular …, 2014 - Wiley Online Library
The function of micro RNA s (mi RNA s) during alcoholic liver disease (ALD) has recently
become of great interest in biological research. Studies have shown that ALD associated mi …

Post-translational modifications of histone and non-histone proteins in epigenetic regulation and translational applications in alcohol-associated liver disease …

W Rungratanawanich, JW Ballway, X Wang… - Pharmacology & …, 2023 - Elsevier
Epigenetic regulation is a process that takes place through adaptive cellular pathways
influenced by environmental factors and metabolic changes to modulate gene activity with …

The epigenetic landscape of alcoholism

HR Krishnan, AJ Sakharkar, TL Teppen… - International Review of …, 2014 - Elsevier
Alcoholism is a complex psychiatric disorder that has a multifactorial etiology. Epigenetic
mechanisms are uniquely capable of accounting for the multifactorial nature of the disease …

High glucose induces lipid accumulation via 25-hydroxycholesterol DNA-CpG methylation

Y Wang, L Chen, WM Pandak, D Heuman, PB Hylemon… - Iscience, 2020 - cell.com
This work investigates the relationship between high-glucose (HG) culture, CpG methylation
of genes involved in cell signaling pathways, and the regulation of carbohydrate and lipid …

[HTML][HTML] Epigenetic effects of ethanol on the liver and gastrointestinal system

SD Shukla, RW Lim - Alcohol research: current reviews, 2013 - ncbi.nlm.nih.gov
The widening web of epigenetic regulatory mechanisms also encompasses ethanol-induced
changes in the gastrointestinal (GI)–hepatic system. In the past few years, increasing …

Past, present, and future of chemically induced hepatocarcinogenesis rodent models: Perspectives concerning classic and new cancer hallmarks

GR Romualdo, R Heidor, GP Bacil, FS Moreno… - Life Sciences, 2023 - Elsevier
Hepatocellular carcinoma (HCC), the main primary liver cancer, accounts for 5% of all
incident cases and 8.4% of all cancer-related deaths worldwide. HCC displays a spectrum of …

Insights into the roles of epigenetic modifications in ferroptosis

J Kong, H Lyu, Q Ouyang, H Shi, R Zhang, S Xiao… - Biology, 2024 - mdpi.com
Simple Summary Since ferroptosis was proposed in 2012, it has been a popular field of
study for researchers. So far, the regulatory mechanism of ferroptosis involves many …