Abstract Changes in gene expression are involved in many brain functions. Epigenetic processes modulate gene expression by histone modification and DNA methylation or RNA …
Somatic mutations in nonmalignant tissues accumulate with age and injury, but whether these mutations are adaptive on the cellular or organismal levels is unclear. To interrogate …
K McDaniel, L Herrera, T Zhou… - Journal of cellular …, 2014 - Wiley Online Library
The function of micro RNA s (mi RNA s) during alcoholic liver disease (ALD) has recently become of great interest in biological research. Studies have shown that ALD associated mi …
Epigenetic regulation is a process that takes place through adaptive cellular pathways influenced by environmental factors and metabolic changes to modulate gene activity with …
Alcoholism is a complex psychiatric disorder that has a multifactorial etiology. Epigenetic mechanisms are uniquely capable of accounting for the multifactorial nature of the disease …
Y Wang, L Chen, WM Pandak, D Heuman, PB Hylemon… - Iscience, 2020 - cell.com
This work investigates the relationship between high-glucose (HG) culture, CpG methylation of genes involved in cell signaling pathways, and the regulation of carbohydrate and lipid …
The widening web of epigenetic regulatory mechanisms also encompasses ethanol-induced changes in the gastrointestinal (GI)–hepatic system. In the past few years, increasing …
Hepatocellular carcinoma (HCC), the main primary liver cancer, accounts for 5% of all incident cases and 8.4% of all cancer-related deaths worldwide. HCC displays a spectrum of …
J Kong, H Lyu, Q Ouyang, H Shi, R Zhang, S Xiao… - Biology, 2024 - mdpi.com
Simple Summary Since ferroptosis was proposed in 2012, it has been a popular field of study for researchers. So far, the regulatory mechanism of ferroptosis involves many …