Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

High-throughput studies of biological systems are rapidly accumulating a wealth of'omics'-
scale data. Visualization is a key aspect of both the analysis and understanding of these …

Availability of large-scale experimental data for cell biology is enabling computational
methods to systematically model the behaviour of cellular networks. This review surveys the …

Computational analysis of biomolecular interaction networks is now gaining a lot of
importance to understand the functions of novel genes/proteins. Gene interaction (GI) …

One of the challenges raised by next generation sequencing (NGS) is the identification of
clinically relevant mutations among all the genetic variation found in an individual. Network …

Abstract Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …

Abstract “Α picture is worth a thousand words.” This widely used adage sums up in a few
words the notion that a successful visual representation of a concept should enable easy …

Background In recent years, mammalian protein-protein interaction network databases have
been developed. The interactions in these databases are either extracted manually from low …

We present an algorithm for the layout of undirected compound graphs, relaxing restrictions
of previously known algorithms in regards to topology and geometry. The algorithm is based …

Understanding the structure and the dynamics of the complex intercellular network of
interactions that contributes to the structure and function of a living cell is one of the main …