Nanotherapy has emerged as an improved anticancer therapeutic strategy to circumvent the
harmful side effects of chemotherapy. It has been proven to be beneficial to offer multiple …

The production of therapeutic recombinant toxins requires careful host cell selection.
Bacteria, yeast, and mammalian cells are common choices, but no universal solution exists …

A novel suicide gene therapy approach was tested in U87 MG glioblastoma multiforme cells.
A 26nt G-rich double-stranded DNA aptamer (AS1411) was integrated into a vector at the …

The delivery of therapeutics across the cell membrane and into the cytoplasm is a major
challenge that limits the development of new therapies. This challenge is compounded by …

Ribosome-inactivating proteins, including Saporin toxin, have found application in the
search for innovative alternative cancer therapies to conventional chemo-and radiotherapy …

Chemotherapy, a conventional breast cancer treatment, has limitations due to its non-
specific mechanisms and undesirable side effects. Lipid-based nanoparticles (LNPs) have …

Breast cancer, a heterogeneous and complex disease, remains a significant healthcare
challenge around the world, with drug resistance being a major impediment to successful …

Gene therapy was developed for treating metabolic disorders where a naturally defective
gene (mutated or deleted) in cells is rectified by delivering an equivalent functional full …