Because it is only possible to test chemicals for effects on a restricted range of species and
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …

Despite advances in toxicity testing and the development of new approach methodologies
(NAMs) for hazard assessment, the ecological risk assessment (ERA) framework for …

The initial step in the assessment of the ecological risk of pollutants is to determine the
predicted no-effect concentration (PNEC). However, ecological risk assessments of eight …

Alkylphenols (APs) are ubiquitous and generally present in higher residue levels in the
environment. The present work focuses on the development of a set of in silico models to …

Species sensitivity distributions (SSDs) are used in ecological risk assessment for
extrapolation of the results of toxicity tests with single species to a toxicity threshold …

The mode of toxic action (MOA) has been recognized as a key determinant of chemical
toxicity and as an alternative to chemical class-based predictive toxicity modeling. However …

Difenoconazole is a typical triazole fungicide that can inhibit demethylation during ergosterol
synthesis. Due to its wide use, difenoconazole is frequently detected in surface water, paddy …

Freshwater mussels, one of the most imperiled groups of animals in the world, are generally
underrepresented in toxicity databases used for the development of ambient water quality …

Toxicological information as needed for risk assessments of chemical compounds is often
sparse. Unfortunately, gathering new toxicological information experimentally often involves …

Due to their endocrine-disrupting effects and the risks posed in surface waters, in particular
by chronic low-dose exposure to aquatic organisms, phthalate esters (PAEs) have received …