Myeloid cell production within the bone marrow is accelerated in the setting of cancer, and
the numbers of circulating and infiltrating neutrophils and granulocytic myeloid derived …

Abstract Multimerin-1 (MMRN1) is a platelet protein with a role in haemostasis and
coagulation. It is also present in endothelial cells (ECs) and the extracellular matrix (ECM) …

Background Gastric cancer is one of the deadliest cancers, currently available therapies
have limited success. Cancer-associated fibroblasts (CAFs) are pivotal cells in the stroma of …

Background The contribution of the tumor microenvironment and extracellular matrix to the
aggressive biology of Gastric Cancer (GC) has been recently characterized; however, the …

Alterations in extracellular matrix (ECM) components that modulate inflammatory cell
behavior have been shown to serve as early starters for multifactorial diseases such as …

Colon cancer is one of the first tumor types where a functional link between inflammation
and tumor onset has been described; however, the microenvironmental cues affecting colon …

Background Globally, the incidence and mortality rates of gastric cancer are high, and its
poor prognosis is closely related to tumor recurrence and metastasis. Therefore, the …

The peritoneal cavity, especially the omentum, is a common site for gastric cancer
metastasis, representing advanced disease stage and poor prognosis. Here, we studied the …

Supramolecular extracellular matrix (ECM) networks play an essential role in skin
architecture and function. Elastin microfibril interface-located proteins (EMILINs) comprise a …

Several studies have demonstrated that melanoma-derived extracellular vesicles (EVs) are
involved in lymph node metastasis; however, the molecular mechanisms involved are not …