Porcine circoviruses: current status, knowledge gaps and challenges

T Opriessnig, AK Karuppannan, AMMG Castro… - Virus research, 2020 - Elsevier
Circoviruses (CV) include some of the smallest viruses known. They were named after their
circularly arranged single-stranded DNA genome with a gene encoding a conserved …

Porcine circovirus type 2 (PCV2) vaccines in the context of current molecular epidemiology

AK Karuppannan, T Opriessnig - Viruses, 2017 - mdpi.com
Porcine circovirus type 2 (PCV2) is an economically important swine pathogen and,
although small, it has the highest evolution rate among DNA viruses. Since the discovery of …

S1 gene-based phylogeny of infectious bronchitis virus: an attempt to harmonize virus classification

V Valastro, EC Holmes, P Britton, A Fusaro… - Infection, Genetics and …, 2016 - Elsevier
Infectious bronchitis virus (IBV) is the causative agent of a highly contagious disease that
results in severe economic losses to the global poultry industry. The virus exists in a wide …

Porcine circovirus 2 (PCV-2) genotype update and proposal of a new genotyping methodology

G Franzo, J Segalés - PloS one, 2018 - journals.plos.org
Porcine circovirus 2 (PCV-2) is one of the most widespread viral infections of swine, causing
a remarkable economic impact because of direct losses and indirect costs for its control. As …

Global molecular genetic analysis of porcine circovirus type 2 (PCV2) sequences confirms the presence of four main PCV2 genotypes and reveals a rapid increase of …

CT Xiao, PG Halbur… - Journal of General …, 2015 - microbiologyresearch.org
The oldest porcine circovirus type 2 (PCV2) sequence dates back to 1962 and is among
several hundreds of publicly available PCV2 sequences. Despite this resource, few studies …

Porcine circovirus 2 genotypes, immunity and vaccines: Multiple genotypes but one single serotype

G Franzo, J Segalés - Pathogens, 2020 - mdpi.com
Identified for the first time in the 1990s, Porcine circovirus 2 (PCV-2) should not be
considered an emerging virus anymore. Nevertheless, many aspects of its biology and …

The natural history of porcine circovirus type 2: from an inoffensive virus to a devastating swine disease?

J Segalés, T Kekarainen, M Cortey - Veterinary microbiology, 2013 - Elsevier
The present review summarizes the current knowledge on the natural history of porcine
circovirus type 2 (PCV2) infection and its related diseases. The perception about PCV2 as a …

Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2)

NM Beach, XJ Meng - Virus research, 2012 - Elsevier
Porcine circovirus type 2 (PCV2) is the causative agent of an economically significant
collection of disease syndromes in pigs, now known as porcine circovirus associated …

Origin, genetic diversity, and evolutionary dynamics of novel porcine circovirus 3

G Li, W He, H Zhu, Y Bi, R Wang, G Xing… - Advanced …, 2018 - Wiley Online Library
Abstract Porcine circovirus 3 (PCV3) is a novel virus associated with acute PDNS (porcine
dermatitis and nephropathy syndrome)‐like clinical signs identified by metagenomic …

Concurrent infections are important for expression of porcine circovirus associated disease

T Opriessnig, PG Halbur - Virus research, 2012 - Elsevier
Porcine circovirus type 2 (PCV2) is the essential component of porcine circovirus disease
(PCVD) as the disease syndrome is referred to in Europe and porcine circovirus associated …