Trends in the synthesis of polymer nano‐and microscale materials for bio‐related applications

JP Coats, R Cochereau, IA Dinu… - Macromolecular …, 2023 - Wiley Online Library
Polymeric nano‐and microscale materials bear significant potential in manifold applications
related to biomedicine. This is owed not only to the large chemical diversity of the constituent …

Poly (2-oxazoline) with Pendant Hydroxyl Groups via a Silyl Ether-Based Protecting Group

J Kim, V Beyer, CR Becer - Macromolecules, 2022 - ACS Publications
The introduction of a functionality onto a poly (2-oxazoline)(POx) chain has been widely
explored, yet reports of POx bearing hydroxyl side chains in a well-defined manner have not …

Facile Generation of Heterotelechelic Poly (2‐Oxazoline) s Towards Accelerated Exploration of Poly (2‐Oxazoline)‐Based Nanomedicine

JFR Van Guyse, S Abbasi, K Toh… - Angewandte …, 2024 - Wiley Online Library
Controlling the end‐groups of biocompatible polymers is crucial for enabling polymer‐based
therapeutics and nanomedicine. Typically, end‐group diversification is a challenging and …

Folic Acid-Conjugated Brush Polymers Show Enhanced Blood–Brain Barrier Crossing in Static and Dynamic In Vitro Models Toward Brain Cancer Targeting Therapy

ZAI Mazrad, A Refaat, JP Morrow… - ACS Biomaterials …, 2024 - ACS Publications
Over the past decades, evidence has consistently shown that treatment of central nervous
system (CNS)-related disorders, including Alzheimer's disease, Parkinson's disease, stroke …

Schiff-Base Cross-Linked Poly (2-oxazoline) Micelle Drug Conjugates Possess Antiferroptosis Activity in Numerous In Vitro Cell Models

JP Morrow, ZAI Mazrad, NM Warne, S Ayton… - …, 2024 - ACS Publications
A great deal of nanocarriers have been applied to induce ferroptosis in cancer research, yet
there are limited examples of nanocarrier formulations to rescue ferroptosis, which can be …

[HTML][HTML] End-functionalized diblock copolymers by mix and match of poly (2-oxazoline) and polyester building blocks

LM Stafast, N Engel, H Görls, C Weber… - European Polymer …, 2023 - Elsevier
Abstract 2-(4-(Iodomethyl) benzyl) isoindoline-1, 3-dione was utilized as a protected amine-
functionalized initiator for the cationic ring opening-polymerization (CROP) of 2-ethyl-2 …

Comparison of the Anti-inflammatory Activity and Cellular Interaction of Brush Polymer–N-Acetyl Cysteine Conjugates in Human and Murine Microglial Cell Lines

ZAI Mazrad, MN Leiske, RF Tabor… - Molecular …, 2023 - ACS Publications
Microglia-mediated neuroinflammation is commonly associated with neurodegeneration and
has been implicated in several neurological disorders, such as Alzheimer's disease and …

[图书][B] Scalable Fabrication of Micro-Architected Water Filtering Membranes

AC Friedman - 2023 - search.proquest.com
Polymer-based filtration devices are predominantly mass manufactured via mechanical
spinning or electrospinning of heated polymer materials or fiberglass to create a randomly …