Background Coumarins, abundantly distributed in a plethora of biologically active
compounds, serve as a fundamental motif in numerous natural products, drugs, and …

Natural coumarins and isocoumarins show significant therapeutic potential against cancer in
preclinical studies by targeting multiple pathways and processes. These compounds …

Herein, we report an efficient and eco-friendly, ultrasound assisted synthetic strategy for the
construction of diversified pyrrolobenzodiazepine-triazole hybrids, which are potentially …

Twelve novel neo-tanshinlactone–chalcone hybrid molecules were constructed through a
versatile methodology involving the Horner–Wadsworth–Emmons (HWE) olefination of 4 …

Herein, we present a one‐pot, three‐component synthesis of spirooxindole‐oxofuran
carboxylate derivatives (4 a–d) through the Huisgen reaction. The newly synthesized …

A visible light-promoted, efficient, green, and sustainable strategy has been adopted to
unlatch a new pathway toward the synthesis of a library of medicinally important 4, 4 …

A new and highly efficient visible-light-promoted catalyst free (VLCF) strategy for neat and
clean synthesis of spiro indolo-quinazolinone-pyrrolo [3, 4-a] pyrrolizine hybrids (6a–d) has …

An efficient synthetic route to construct diverse pyrazole-based chalcones from 1-phenyl-1 H-
pyrazol-3-ols bearing a formyl or acetyl group on the C4 position of pyrazole ring, employing …

Chalcones are small molecules, naturally found in fruits and vegetables, and exhibit diverse
pharmacological activities. They also possess anticancer activity against different tumors …

Globally, breast cancer (BC) has the highest prevalence among malignant diseases. BC is
also the primary cause of death among women. Notably, BC morbidity has been increasing …