Abstract The 1, 3, 4‐oxadiazole nucleus is a biologically imperative scaffold possesses
numerous biological activities. The broad and potent activity of 1, 3, 4‐oxadiazole and their …

The oxadiazole core is considered a privileged moiety in many medicinal chemistry
applications. The oxadiazole class includes 1, 2, 3-oxadiazole, 1, 2, 4-oxadiazole, 1, 3, 4 …

A series of new benzothiazole-1, 3, 4-oxadiazole-4-thiazolidinone hybrid analogs (Tz1-
Tz28) were synthesized in search of potential anti-diabetic agents. Molecular docking study …

Cancer is one of the most prominent causes of death worldwide and tubulin is a crucial
protein of cytoskeleton that maintains essential cellular functions including cell division as …

A novel library of chalcone linked thiazole-imidazopyridine (12a–j) derivatives were
designed, synthesized, and their structures were characterized by 1 H NMR, 13 C NMR and …

A series of ten novel 2, 5-bis (indolyl)-1, 3, 4-oxadiazoles were designed and synthesized.
All these compounds were evaluated for their cytotoxicity against four cancer cell lines …

A novel library of amide functionality having 1, 2, 4-thiadiazole-1, 2, 4-triazole (8a–j) analogs
was designed, synthesized, and structures were characterized by 1 H NMR, 13 C NMR, and …

A new series of benzimidazole/benzoxazole linked β-carbolines (9a-j) were rationally
designed and synthesized by combining two different anti-cancer fragments. The new hybrid …

Theoretical calculations were used to optimize molecular structures which help determine
binding energies, and elucidate electronic properties of unsubstituted benzothiazole (BTH) …

Carbazole is an important type of tricyclic nitrogen containing compound and isolated first
from coal tar in 1872 by Graebe and Glazer. Carbazole alkaloids have received …