The Royal Ulster Constabulary is the police force responsible for the maintenance of law
and order in Northern Ireland. To appreciate its policy and understand the significance of its …

Chronic itch poses major health care and economic burdens worldwide. In 2013, B‐type
natriuretic peptide (BNP) was identified as an itch‐selective neuropeptide and shown to be …

The aim of the present study was to explore the mechanisms underlyin}; the renal effects of
caffeine. 2. Male Sprague-Dawley rats were treated with catTeine, consisting of a single oral …

ANG II arrests LLC-PK1 cells in the G1 phase of the cell cycle and induces hypertrophy, an
effect mediated by induction of p27Kip1. We studied whether atrial natriuretic peptide (ANP) …

Increased expression of atrial natriuretic peptide in the kidney of rats with bilateral ureteral
obstruction. Background Whether the postobstructive diuresis can be related to an altered …

Morphological changes of the tubulointerstitial architecture are a major determinant in the
progression of chronic renal disease. The evolution of the tubulointerstitial lesion includes …

Aims: Effects of the blockade of renin-angiotensin system (RAS), by angiotensin-converting
enzyme inhibitor (ACEi), type 1 angiotensin II receptor blocker (ARB), or a combination of …

The generation and function (s) of the signalling molecule cyclic GMP (cGMP) in brain are
still poorly understood. One mechanism to raise intracellular cGMP levels is binding of C …

Abstract We have isolated a 3.9-kbp-long cDNA and approximately 93 kbp long genomic
DNA encoding a membrane guanylyl cyclase (designated OlGCl) from the medaka fish …

The present study was aimed at investigating whether the regulation of vascular renin–
angiotensin and endothelin (ET) systems is altered by a chronic blockade of nitric oxide …