[HTML][HTML] Progression from early/intermediate to advanced forms of age-related macular degeneration in a large UK cohort: rates and risk factors

U Chakravarthy, CC Bailey, PH Scanlon… - Ophthalmology …, 2020 - Elsevier
Purpose To estimate rates and risk factors for progression to geographic atrophy (GA) or
choroidal neovascularization (CNV) among eyes diagnosed with early or intermediate age …

[HTML][HTML] Topographic variation of the growth rate of geographic atrophy in nonexudative age-related macular degeneration: a systematic review and meta-analysis

LL Shen, M Sun, S Khetpal, HKG Nardini… - … & Visual Science, 2020 - tvst.arvojournals.org
Purpose: To determine the impact of topographic locations on the progression rate of
geographic atrophy (GA). Methods: We searched in five literature databases up to May 3 …

Growth rate of geographic atrophy secondary to age-related macular degeneration: a meta-analysis of natural history studies and implications for designing future …

J Wang, GS Ying - Ophthalmic Research, 2021 - karger.com
Introduction: There is no effective treatment for geographic atrophy (GA). To help design
future GA treatment trials, we conducted a meta-analysis for GA growth rate and its variability …

Fundus autofluorescence and optical coherence tomography biomarkers associated with the progression of geographic atrophy secondary to age-related macular …

PTA Bui, GS Reiter, M Fabianska, SM Waldstein… - Eye, 2022 - nature.com
Objectives To investigate the impact of qualitatively graded and deep learning quantified
imaging biomarkers on growth of geographic atrophy (GA) secondary to age-related …

Geographic atrophy growth is strongly related to lesion perimeter: unifying effects of lesion area, number, and circularity on growth

LL Shen, M Sun, A Ahluwalia, BK Young, MM Park… - Ophthalmology …, 2021 - Elsevier
Purpose To investigate the underlying reason for the previously observed impact of baseline
lesion size, number, and circularity on geographic atrophy (GA) growth rate. Design …

Long-term natural history of visual acuity in eyes with choroideremia: a systematic review and meta-analysis of data from 1004 individual eyes

LL Shen, A Ahluwalia, M Sun, BK Young… - British Journal of …, 2021 - bjo.bmj.com
Background/aims Best-corrected visual acuity (BCVA) is the most common primary endpoint
in treatment trials for choroideremia (CHM) but the long-term natural history of BCVA is …

Natural history of autosomal recessive Stargardt disease in untreated eyes: a systematic review and meta-analysis of study-and individual-level data

LL Shen, M Sun, HKG Nardini, LV Del Priore - Ophthalmology, 2019 - Elsevier
Topic Systematic review and meta-analysis of the natural history of autosomal recessive
Stargardt disease (STGD1). Clinical Relevance Controversy exists regarding the …

Relationship of topographic distribution of geographic atrophy to visual acuity in nonexudative age-related macular degeneration

LL Shen, M Sun, A Ahluwalia, BK Young, MM Park… - Ophthalmology …, 2021 - Elsevier
Purpose To investigate the topographic distribution of geographic atrophy (GA) and to
identify an anatomic endpoint that correlates with visual acuity (VA) in eyes with GA. Design …

Progression of unifocal versus multifocal geographic atrophy in age-related macular degeneration: a systematic review and meta-analysis

LL Shen, M Sun, HKG Nardini, LV Del Priore - Ophthalmology Retina, 2020 - Elsevier
Topic Determining the natural history of unifocal versus multifocal geographic atrophy (GA)
secondary to nonexudative age-related macular degeneration. Clinical Relevance The …

Reclassification of fundus autofluorescence patterns surrounding geographic atrophy based on progression rate: a systematic review and meta-analysis

LL Shen, F Liu, HG Nardini, LV Del Priore - Retina, 2019 - journals.lww.com
Purpose: To reclassify fundus autofluorescence (FAF) patterns around geographic atrophy
(GA) based on GA progression rates. Methods: MEDLINE, EMBASE, Cochrane Library …