Background Substance use is a public crisis in the US Substance use can be understood as
a series of events in the life course, from initiation to mortality. Social Determinants of Health …

The widespread use of opioids for chronic pain management not only poses a significant
public health issue but also contributes to the risk of tolerance, dependence, and addiction …

CONTEXT Opioid-related harms continue to rise for children and youth. Analgesic
prescribing decisions are challenging because the risk for future nonmedical opioid use or …

Can positive transitions into young adulthood at age 25 prevent problematic substance use
at age 31, even in the context of childhood adverse family environments, conduct problems …

From a developmental perspective, the increase in depressive symptoms among
adolescents over the past decade is of great concern due to the risk of long-term mental …

Background: The opioid crisis is an ongoing public health crisis affecting all segments of
society, including youth. However, there is limited research available on strategies that youth …

Objective This study compared female adolescents in institutional care (AICs) diagnosed
with major depression (MD) or substance use disorder (SUD) with those who were not. In …

The opioid crisis has emphasized identification of opioid‐sparing analgesics. This study was
designed as a prospective trial with retrospective control group to determine feasibility for …

Objective Early identification of substance use during adolescence is imperative to reduce
the risk of morbidity and mortality. The aim of this study was to determine the utility of the …

Background: US studies suggest a positive association between attention deficit–
hyperactivity disorder (ADHD) and the risk of exposure to prescription opioids. However …