Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema.
This disease impairs patients' quality of life enormously. Pathological findings demonstrate …

Inflammatory arthritis are common chronic inflammatory autoimmune diseases characterised
by progressive, destructive inflammation of the joints leading to a loss of function and …

Several mediators including cytokines, growth factors and metalloproteinases (MMP)
modulate pathological angiogenesis associated with inflammatory arthritis. The biological …

Abstract Objective In psoriatic arthritis (PsA) and rheumatoid arthritis (RA), inflammatory
responses are characterized by increased production of pro-inflammatory molecules …

Objectives A number of immune populations have been implicated in psoriatic arthritis (PsA)
pathogenesis. This study used mass cytometry (CyTOF) combined with transcriptomic …

Single cell RNA sequencing (scRNA-seq) represents a new large scale and high throughput
technique allowing analysis of the whole transcriptome at the resolution of an individual cell …

Autoimmune diseases are complex conditions characterized by immune-mediated tissue
damage and chronic inflammation. Protease-activated receptor 2 (Par2) has been …

Protease-activated receptor-2 (PAR2) is a class-A G protein-coupled receptor (GPCR)
activated by serine proteases and is expressed by multiple tissues, including the skin. PAR2 …

Introduction Psoriasis (PSO) and psoriatic arthritis (PSA) represent a large burden of global
inflammatory disease, but sustained treatment response and early diagnosis remain …

Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy affecting the skin, entheses,
and joints. Over the past decade, experimental evidence has revealed the activation of …