The Wnt/β-catenin signaling pathway exerts integral roles in embryogenesis and adult
homeostasis. Aberrant activation of the pathway is implicated in growth-associated diseases …

Cancer as we know it is actually an umbrella term for over 100 very unique malignancies in
various tissues throughout the human body. Each type, and even subtype of cancer, has …

Peptide-based drug discovery has experienced a significant upturn within the past decade
since the introduction of chemical modifications and unnatural amino acids has allowed for …

The non-enzymatic functions of target proteins play key roles in the regulation of various cell
signaling pathways and are closely related to numerous human diseases. However …

Abnormal DNA methylation is an important epigenetic regulator involving tumorigenesis.
Deciphering cancer common and specific DNA methylation patterns is essential for us to …

Glomerular endothelial cell (GEnC) dysfunction is important in the pathogenesis of
glomerular sclerotic diseases, including Focal Segmental Glomerulosclerosis (FSGS) and …

PRC2 is a therapeutic target for several types of cancers currently undergoing clinical trials.
Its activity is regulated by a positive feedback loop whereby its terminal enzymatic product …

Enhancer of zeste homolog 2 inhibitors (EZH2i) have garnered increased attention owing to
their anticancer activity by targeting EZH2, a well-known cancer-promoting factor. However …

Purpose: Diabetic retinopathy (DR) remains a pressing issue worldwide. Abnormal
angiogenesis is a distinct vascular lesion in DR, and research has established that vascular …

Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …