[HTML][HTML] Mucosal healing and inflammatory bowel disease: Therapeutic implications and new targets

ML Otte, RL Tamang, J Papapanagiotou… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Mucosal healing (MH) is vital in maintaining homeostasis within the gut and protecting
against injury and infections. Multiple factors and signaling pathways contribute in a …

Understanding the complex milieu of epithelial-mesenchymal transition in cancer metastasis: new insight into the roles of transcription factors

SO Imodoye, KA Adedokun, AO Muhammed… - Frontiers in …, 2021 - frontiersin.org
Epithelial-mesenchymal transition (EMT) is a physiological program during which polarised,
immobile epithelial cells lose connection with their neighbours and are converted to …

Hydrogel viscoelasticity modulates migration and fusion of mesenchymal stem cell spheroids

DT Wu, M Diba, S Yang, BR Freedman… - Bioengineering & …, 2023 - Wiley Online Library
Multicellular spheroids made of stem cells can act as building blocks that fuse to capture
complex aspects of native in vivo environments, but the effect of hydrogel viscoelasticity on …

A novel bioswitchable miRNA mimic delivery system: therapeutic strategies upgraded from tetrahedral framework nucleic acid system for fibrotic disease treatment and …

Y Jiang, S Li, R Shi, W Yin, W Lv, T Tian… - Advanced …, 2024 - Wiley Online Library
There has been considerable interest in gene vectors and their role in regulating cellular
activities and treating diseases since the advent of nucleic acid drugs. MicroRNA (miR) …

Overview on the role of E-cadherin in gastric cancer: dysregulation and clinical implications

H Zhao, H Hu, B Chen, W Xu, J Zhao… - Frontiers in Molecular …, 2021 - frontiersin.org
Gastric cancer is the fifth most common cancer and the third most common cause of cancer
death all over the world. E-cadherin encoded by human CDH1 gene plays important roles in …

The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment

H Cessna, S Baritaki, A Zaravinos, B Bonavida - Cancers, 2022 - mdpi.com
Simple Summary Raf kinase inhibitor protein (RKIP) expression in cancer cells is
significantly reduced and promoting cancer cells growth and invasiveness. Overexpresssion …

The effect of mesenchymal stem cells-derived exosomes on the prostate, bladder, and renal cancer cell lines

AR Rezaeian, F Khatami, S Heidari Keshel… - Scientific Reports, 2022 - nature.com
We aimed to explain the role of mesenchymal stem cells (MSC-exosomes) on gene
expressions of epithelial to mesenchymal transition (EMT), angiogenesis, and apoptosis …

Time to go: neural crest cell epithelial-to-mesenchymal transition

TA Leathers, CD Rogers - Development, 2022 - journals.biologists.com
Neural crest cells (NCCs) are a dynamic, multipotent, vertebrate-specific population of
embryonic stem cells. These ectodermally-derived cells contribute to diverse tissue types in …

Regulation of partial and reversible endothelial-to-mesenchymal transition in angiogenesis

JS Fang, NW Hultgren, CCW Hughes - Frontiers in Cell and …, 2021 - frontiersin.org
During development and in several diseases, endothelial cells (EC) can undergo complete
endothelial-to-mesenchymal transition (EndoMT or EndMT) to generate endothelial-derived …

Cadherin signaling in cancer and autoimmune diseases

M Sisto, D Ribatti, S Lisi - International Journal of Molecular Sciences, 2021 - mdpi.com
Cadherins mediate cell–cell adhesion through a dynamic process that is strongly dependent
on the cellular context and signaling. Cadherin regulation reflects the interplay between …