IL-17 (IL-17A) is a pro-inflammatory cytokine produced by a sub-set of T helper cells termed
Th17 cells primarily in response to cytokines like TGF-β and IL-23 and play an important role …

Systemic sclerosis (SSc, scleroderma) is a multifaceted rare connective tissue disease
whose pathogenesis is dominated by immune dysregulation, small vessel vasculopathy …

Systemic sclerosis is a fibrotic disease that initiates in the skin and progresses to internal
organs, leading to a poor prognosis. Unraveling the etiology of a chronic, multifactorial …

Retinal degenerative diseases are a leading cause of vision loss and blindness throughout
the world, characterized by chronic and progressive loss of neurons and/or myelin. One of …

Systemic sclerosis is a multisystemic disease for which the heart can be affected leading to
cardiac complications and mortality. Up to 80% of patients with systemic sclerosis have …

Interleukin 17F (IL17F) has been found to be involved in various inflammatory pathologies
and has recently become a target for therapeutic purposes. In contrast to IL17F secreted by …

Systemic sclerosis (SSc) is a chronic disease characterized by microvasculopathy,
autoantibodies (autoAbs), and fibrosis. The pathogenesis of the disease is incompletely …

In recent years, rapid advances in research methods have made single cell analysis
possible. Systemic sclerosis (SSc), a disease characterized by the triad of immune …

Liver fibrosis is a terminal manifestation of various chronic liver diseases. There are no
drugs that can reverse the condition. Recently, the importance of interleukin-17 (IL17) in the …

B cells play a central role in the pathogenesis of systemic sclerosis (SSc). Most B-cell
studies have focused on their pathological role as antibody producers. However, in addition …