The interaction of bacterial pathogens with platelets

JR Fitzgerald, TJ Foster, D Cox - Nature Reviews Microbiology, 2006 - nature.com
In recent years, the frequency of serious cardiovascular infections such as endocarditis has
increased, particularly in association with nosocomially acquired antibiotic-resistant …

The role of platelets in the pathogenesis of viral hemorrhagic fevers

JC Zapata, D Cox, MS Salvato - PLoS neglected tropical diseases, 2014 - journals.plos.org
Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause
platelet destruction or dysfunction. Here we present the four major ways viruses affect …

Adenovirus-induced thrombocytopenia: the role of von Willebrand factor and P-selectin in mediating accelerated platelet clearance

M Othman, A Labelle, I Mazzetti, HS Elbatarny… - Blood, 2007 - ashpublications.org
Thrombocytopenia has been consistently reported following the administration of adenoviral
gene transfer vectors. The mechanism underlying this phenomenon is currently unknown. In …

Platelets and viruses: an ambivalent relationship

C Flaujac, S Boukour, E Cramer-Bordé - Cellular and molecular life …, 2010 - Springer
Thrombocytopenia is a frequent complication of viral infections providing evidence that
interaction of platelets with viruses is an important pathophysiological phenomenon. Multiple …

A champion of host defense: a generic large-scale cause for platelet dysfunction and depletion in infection

MJ Page, E Pretorius - Seminars in thrombosis and hemostasis, 2020 - thieme-connect.com
Thrombocytopenia is commonly associated with sepsis and infections, which in turn are
characterized by a profound immune reaction to the invading pathogen. Platelets are one of …

The emerging role of platelets in adaptive immunity

BD Elzey, DL Sprague, TL Ratliff - Cellular immunology, 2005 - Elsevier
Platelets' foremost role in survival is hemostasis. However, a significant quantity of research
has demonstrated that platelets are an integral part of inflammation and can also be potent …

Role of Chlamydia pneumoniae in atherosclerosis

C Watson, NJ Alp - Clinical Science, 2008 - portlandpress.com
Cardiovascular disease, resulting from atherosclerosis, is a leading cause of global
morbidity and mortality. Genetic predisposition and classical environmental risk factors …

Hospitalization for infection and risk of acute ischemic stroke: the Cardiovascular Health Study

MSV Elkind, CL Carty, ES O'Meara, T Lumley… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Little is known about the acute precipitants of ischemic stroke,
although evidence suggests infections contribute to risk. We hypothesized that acute …

Why now? Moving from stroke risk factors to stroke triggers

MSV Elkind - Current opinion in neurology, 2007 - journals.lww.com
Why now? Moving from stroke risk factors to stroke triggers : Current Opinion in Neurology Why
now? Moving from stroke risk factors to stroke triggers : Current Opinion in Neurology Log in or …

The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes

LM Beaulieu, JE Freedman - Thrombosis research, 2010 - Elsevier
Platelets have been extensively studied as hemostatic regulators, stopping uncontrolled flow
of blood from an injured vessel and allowing for repair. However, multiple studies have …