Nanomedicine fight against antibacterial resistance: an overview of the recent pharmaceutical innovations

NE Eleraky, A Allam, SB Hassan, MM Omar - Pharmaceutics, 2020 - mdpi.com
Based on the recent reports of World Health Organization, increased antibiotic resistance
prevalence among bacteria represents the greatest challenge to human health. In addition …

Peptide design principles for antimicrobial applications

MDT Torres, S Sothiselvam, TK Lu… - Journal of molecular …, 2019 - Elsevier
The increased incidence of bacterial resistance to available antibiotics represents a major
global health problem and highlights the need for novel anti-infective therapies …

Structure–activity relationship of cationic surfactants as antimicrobial agents

C Zhou, Y Wang - Current Opinion in Colloid & Interface Science, 2020 - Elsevier
Cationic surfactants are widely used as antimicrobial agents in various fields. However, the
widespread use of cationic surfactants has caused huge accumulation in environment …

Antimicrobial polymers as therapeutics for treatment of multidrug-resistant Klebsiella pneumoniae lung infection

W Lou, S Venkataraman, G Zhong, B Ding, JPK Tan… - Acta biomaterialia, 2018 - Elsevier
Klebsiella pneumoniae (K. pneumoniae) is one of the most common pathogens in hospital-
acquired infections. It is often resistant to multiple antibiotics (including carbapenems), and …

Self-assembly of peptide nanofibers with chirality-encoded antimicrobial activity

YY Xie, XT Qin, J Zhang, MY Sun, FP Wang… - Journal of Colloid and …, 2022 - Elsevier
The nanostructured antimicrobial agents, self-assembled by the antimicrobial peptides
(AMPs), represent an intriguing platform for the treatment of pathogens. Although the …

Injectable Multifunctional Composite Hydrogel as a Combination Therapy for Preventing Postsurgical Adhesion

K Lv, P Lou, S Liu, Y Wang, J Yang, P Zhou, X Zhou… - Small, 2024 - Wiley Online Library
Postsurgical adhesion (PA) is a common and serious postoperative complication that affects
millions of patients worldwide. However, current commercial barrier materials are insufficient …

Structure-dependent antibacterial activity of amino acid-based supramolecular hydrogels

YY Xie, YW Zhang, XT Qin, LP Liu, F Wahid… - Colloids and Surfaces B …, 2020 - Elsevier
Bacterial infections are currently a major concern to human health. Amino acid-based
supramolecular polymer hydrogels, which boast intrinsic antibacterial activity, are an …

Structure-function relationships of nonviral gene vectors: Lessons from antimicrobial polymers

H Xing, M Lu, T Yang, H Liu, Y Sun, X Zhao, H Xu… - Acta biomaterialia, 2019 - Elsevier
In recent years, substantial advances have been achieved in the design and synthesis of
nonviral gene vectors. However, lack of effective and biocompatible vectors still remains a …

TAT-modified self-assembled cationic peptide nanoparticles as an efficient antibacterial agent

B He, S Ma, G Peng, D He - Nanomedicine: Nanotechnology, Biology and …, 2018 - Elsevier
The increasing emergence of drug resistant pathogenic bacteria poses a great challenge to
clinical therapy and a threat to public health. Cationic peptides have received great attention …

Enhanced antibacterial properties of self-assembling peptide amphiphiles functionalized with heparin-binding cardin-motifs

R Chang, K Subramanian, M Wang… - ACS applied materials …, 2017 - ACS Publications
The emergence of antibiotic resistance in bacteria has caused many healthcare problems
and social burdens. In this study, a type of self-assembled peptide amphiphiles (PA) …