Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

Ras homolog gene family member A (RhoA) is a small GTPase of the Rho family involved in
regulating multiple signal transduction pathways that influence a diverse range of cellular …

Dendritic spines are small protrusions studding neuronal dendrites, first described in 1888
by Ramón y Cajal using his famous Golgi stainings. Around 50 years later the advance of …

The brain constantly adapts to changes in the environment, a capability that underlies
memory and behavior. Long-term adaptations require the remodeling of neural circuits that …

Abstract 22q11. 2 deletion syndrome (22q11. 2DS) is the most common chromosomal
microdeletion disorder, estimated to result mainly from de novo non-homologous meiotic …

The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …

MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …

The proper formation and function of neuronal networks is required for cognition and
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …

Recent studies have revealed that patients with psychiatric disorders have altered
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …

Schizophrenia is a chronic disorder characterized by specific positive and negative primary
symptoms, social behavior disturbances and cognitive deficits (eg, impairment in working …