Forgetting as a form of adaptive engram cell plasticity

TJ Ryan, PW Frankland - Nature Reviews Neuroscience, 2022 - nature.com
One leading hypothesis suggests that memories are stored in ensembles of neurons (or
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …

Bridging biological and artificial neural networks with emerging neuromorphic devices: fundamentals, progress, and challenges

J Tang, F Yuan, X Shen, Z Wang, M Rao… - Advanced …, 2019 - Wiley Online Library
As the research on artificial intelligence booms, there is broad interest in brain‐inspired
computing using novel neuromorphic devices. The potential of various emerging materials …

Incorporating neuro-inspired adaptability for continual learning in artificial intelligence

L Wang, X Zhang, Q Li, M Zhang, H Su, J Zhu… - Nature Machine …, 2023 - nature.com
Continual learning aims to empower artificial intelligence with strong adaptability to the real
world. For this purpose, a desirable solution should properly balance memory stability with …

Distilling causal effect of data in class-incremental learning

X Hu, K Tang, C Miao, XS Hua… - Proceedings of the …, 2021 - openaccess.thecvf.com
We propose a causal framework to explain the catastrophic forgetting in Class-Incremental
Learning (CIL) and then derive a novel distillation method that is orthogonal to the existing …

Engram neurons: Encoding, consolidation, retrieval, and forgetting of memory

A Guskjolen, MS Cembrowski - Molecular psychiatry, 2023 - nature.com
Tremendous strides have been made in our understanding of the neurobiological substrates
of memory–the so-called memory “engram”. Here, we integrate recent progress in the …

Active forgetting: Adaptation of memory by prefrontal control

MC Anderson, JC Hulbert - annual review of psychology, 2021 - annualreviews.org
Over the past century, psychologists have discussed whether forgetting might arise from
active mechanisms that promote memory loss to achieve various functions, such as …

The neurobiological foundation of memory retrieval

PW Frankland, SA Josselyn, S Köhler - Nature neuroscience, 2019 - nature.com
Memory retrieval involves the interaction between external sensory or internally generated
cues and stored memory traces (or engrams) in a process termed 'ecphory'. While ecphory …

The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit

MN Modi, Y Shuai, GC Turner - Annual review of neuroscience, 2020 - annualreviews.org
The Drosophila brain contains a relatively simple circuit for forming Pavlovian associations,
yet it achieves many operations common across memory systems. Recent advances have …

Distinct dopamine receptor pathways underlie the temporal sensitivity of associative learning

A Handler, TGW Graham, R Cohn, I Morantte… - Cell, 2019 - cell.com
Animals rely on the relative timing of events in their environment to form and update
predictive associations, but the molecular and circuit mechanisms for this temporal …

The neurobiology of fear generalization

A Asok, ER Kandel, JB Rayman - Frontiers in behavioral …, 2019 - frontiersin.org
The generalization of fear memories is an adaptive neurobiological process that promotes
survival in complex and dynamic environments. When confronted with a potential threat, an …