Nucleotide excision repair (NER) is the most versatile mechanism of DNA repair,
recognizing and dealing with a variety of helix-distorting lesions, such as the UV-induced …

DNA cruciforms play an important role in the regulation of natural processes involving DNA.
These structures are formed by inverted repeats, and their stability is enhanced by DNA …

The numerous processes that damage DNA are counterbalanced by a complex network of
repair pathways that, collectively, can mend diverse types of damage. Insights into these …

DNA structure functions as an overlapping code to the DNA sequence. Rapid progress in
understanding the role of DNA structure in gene regulation, DNA damage recognition and …

Background Aerobic organisms are susceptible to damage by reactive oxygen species.
Oxidative stress resistance is a quantitative trait with population variation attributable to the …

MEI-9 is the Drosophila homolog of the human structure-specific DNA endonuclease XPF.
Like XPF, MEI-9 functions in nucleotide excision repair and interstrand crosslink repair. MEI …

We review the critical events in early meiotic prophase in Drosophila melanogaster oocytes.
We focus on four aspects of this process: the formation of the synaptonemal complex (SC) …

After reconstitution of nucleotide excision repair (excision repair) with XPA, RPA, XPC, TFIIH,
XPF-ERCC1 and XPG, it was concluded that these six factors are the minimal essential …

Previous work with the classic T4 endonuclease V digestion of DNA from irradiated
Drosophila cells followed by Southern hybridization led to the conclusion that Drosophila …

Recent studies of meiotic recombination in the budding yeast and the model plant
Arabidopsis thaliana indicate that meiotic crossovers (COs) occur through two genetic …