Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA

P Wu, Y Mo, M Peng, T Tang, Y Zhong, X Deng… - Molecular cancer, 2020 - Springer
Non-coding RNAs do not encode proteins and regulate various oncological processes. They
are also important potential cancer diagnostic and prognostic biomarkers. Bioinformatics …

Molecular cogs: interplay between circadian clock and cell cycle

J Gaucher, E Montellier, P Sassone-Corsi - Trends in Cell Biology, 2018 - cell.com
The cell cycle and the circadian clock operate as biological oscillators whose timed
functions are tightly regulated. Accumulating evidence illustrates the presence of molecular …

Viral internal ribosomal entry sites: four classes for one goal

J Mailliot, F Martin - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
To ensure efficient propagation, viruses need to rapidly produce viral proteins after cell
entrance. Since viral genomes do not encode any components of the protein biosynthesis …

Expanding role of ubiquitin in translational control

SE Dougherty, AO Maduka, T Inada… - International journal of …, 2020 - mdpi.com
The eukaryotic proteome has to be precisely regulated at multiple levels of gene expression,
from transcription, translation, and degradation of RNA and protein to adjust to several …

E3 ligases: a potential multi-drug target for different types of cancers and neurological disorders

KM Saravanan, M Kannan, P Meera… - Future Medicinal …, 2022 - Taylor & Francis
Ubiquitylation is a posttranslational modification of proteins that is necessary for a variety of
cellular processes. E1 ubiquitin activating enzyme, E2 ubiquitin conjugating enzyme, and E3 …

Epilepsy and its interaction with sleep and circadian rhythm

B Jin, T Aung, Y Geng, S Wang - Frontiers in Neurology, 2020 - frontiersin.org
Growing evidence shows the bidirectional interactions between sleep, circadian rhythm, and
epilepsy. Comprehending how these interact with each other may help to advance our …

SINEUPs: a novel toolbox for RNA therapeutics

S Espinoza, C Bon, P Valentini, B Pierattini… - Essays in …, 2021 - portlandpress.com
RNA molecules have emerged as a new class of promising therapeutics to expand the
range of druggable targets in the genome. In addition to 'canonical'protein-coding mRNAs …

Expression of a large coding sequence: Gene therapy vectors for Ataxia Telangiectasia

T Hirch, N Brander, F Schenk, SJ Pöllmann… - Scientific Reports, 2023 - nature.com
Ataxia telangiectasia is a monogenetic disorder caused by mutations in the ATM gene. Its
encoded protein kinase ATM plays a fundamental role in DNA repair of double strand …

RPFdb v2. 0: an updated database for genome-wide information of translated mRNA generated from ribosome profiling

H Wang, L Yang, Y Wang, L Chen, H Li… - Nucleic acids …, 2019 - academic.oup.com
Abstract RPFdb (http://www. rpfdb. org or http://sysbio. sysu. edu. cn/rpfdb) is a public
database for hosting, analyzing and visualizing ribosome profiling (ribo-seq) data. Since its …

GWIPS-viz: 2018 update

AM Michel, SJ Kiniry, PBF O'Connor… - Nucleic acids …, 2018 - academic.oup.com
The GWIPS-viz browser (http://gwips. ucc. ie/) is an on-line genome browser which is
tailored for exploring ribosome profiling (Ribo-seq) data. Since its publication in 2014 …