Melatonin, a full service anti-cancer agent: inhibition of initiation, progression and metastasis

RJ Reiter, SA Rosales-Corral, DX Tan… - International journal of …, 2017 - mdpi.com
There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

[HTML][HTML] Melatonin for the prevention and treatment of cancer

Y Li, S Li, Y Zhou, X Meng, JJ Zhang, DP Xu, HB Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
The epidemiological studies have indicated a possible oncostatic property of melatonin on
different types of tumors. Besides, experimental studies have documented that melatonin …

Melatonin: a well‐documented antioxidant with conditional pro‐oxidant actions

HM Zhang, Y Zhang - Journal of pineal research, 2014 - Wiley Online Library
Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine), an indoleamine produced in many
organs including the pineal gland, was initially characterized as a hormone primarily …

Melatonin—A pleiotropic, orchestrating regulator molecule

R Hardeland, DP Cardinali, V Srinivasan… - Progress in …, 2011 - Elsevier
Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …

A review of the molecular aspects of melatonin's anti‐inflammatory actions: recent insights and new perspectives

JL Mauriz, PS Collado, C Veneroso… - Journal of pineal …, 2013 - Wiley Online Library
Melatonin is a highly evolutionary conserved endogenous molecule that is mainly produced
by the pineal gland, but also by other nonendocrine organs, of most mammals including …

Melatonin and cancer hallmarks

WH Talib - Molecules, 2018 - mdpi.com
Melatonin is a natural indoleamine produced by the pineal gland that has many functions,
including regulation of the circadian rhythm. Many studies have reported the anticancer …

Melatonin and stable circadian rhythms optimize maternal, placental and fetal physiology

RJ Reiter, DX Tan, A Korkmaz… - Human reproduction …, 2014 - academic.oup.com
BACKGROUND Research within the last decade has shown melatonin to have previously-
unsuspected beneficial actions on the peripheral reproductive organs. Likewise, numerous …

Protecting the melatonin rhythm through circadian healthy light exposure

MA Bonmati-Carrion, R Arguelles-Prieto… - International journal of …, 2014 - mdpi.com
Currently, in developed countries, nights are excessively illuminated (light at night), whereas
daytime is mainly spent indoors, and thus people are exposed to much lower light intensities …

Breast cancer and circadian disruption from electric lighting in the modern world

RG Stevens, GC Brainard, DE Blask… - CA: a cancer journal …, 2014 - Wiley Online Library
Breast cancer is the leading cause of cancer death among women worldwide, and there is
only a limited explanation of why. Risk is highest in the most industrialized countries but also …

Melatonin: a multitasking molecule

RJ Reiter, DX Tan, L Fuentes-Broto - Progress in brain research, 2010 - Elsevier
Abstract Melatonin (N-acetyl-5-methoxytryptamine) has revealed itself as an ubiquitously
distributed and functionally diverse molecule. The mechanisms that control its synthesis …