Adiponectin and cardiovascular health: an update

X Hui, KSL Lam, PM Vanhoutte… - British journal of …, 2012 - Wiley Online Library
The global epidemic of obesity is accompanied by an increased prevalence of
cardiovascular disease (CVD), in particular stroke and heart attack. Dysfunctional adipose …

Adiponectin receptor signalling in the brain

J Thundyil, D Pavlovski, CG Sobey… - British journal of …, 2012 - Wiley Online Library
Adiponectin is an important adipocyte‐derived hormone that regulates metabolism of lipids
and glucose, and its receptors (AdipoR1, AdipoR2, T‐cadherin) appear to exert actions in …

Role of adiponectin system in insulin resistance

C Caselli - Molecular genetics and metabolism, 2014 - Elsevier
The knowledge of the pathogenesis of obesity and its metabolic sequelae has significantly
advanced over the last few decades and adipose tissue is now considered a link between …

Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin

KKY Cheng, KSL Lam, B Wang, A Xu - Best practice & research Clinical …, 2014 - Elsevier
Adiponectin is an insulin-sensitizing adipokine with protective effects against a cluster of
obesity-related metabolic and cardiovascular disorders. The adipokine exerts its insulin …

[HTML][HTML] The role of adiponectin in periodontitis: Current state and future prospects

Z Wang, Z Chen, F Fang, W Qiu - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Adiponectin (APN), which is an adipokine primarily secreted by adipose tissue into the
peripheral blood, exerts anti-inflammatory and metabolic regulatory functions in many …

Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors

JT Heiker, D Kosel, AG Beck-Sickinger - 2010 - degruyter.com
The adipocytokine adiponectin and its receptor (AdipoR) comprise a new receptor-ligand
system that is involved in a variety of clinically important morbidities such as obesity, type 2 …

[HTML][HTML] Adiponectin receptor binding proteins–recent advances in elucidating adiponectin signalling pathways

C Buechler, J Wanninger, M Neumeier - FEBS letters, 2010 - Elsevier
Adiponectin whose systemic levels are reduced in obesity-related diseases ameliorates
insulin sensitivity and regulates biological processes like apoptosis, proliferation, migration …

Adiponectin receptor 1-mediated stimulation of Cav3. 2 channels in trigeminal ganglion neurons induces nociceptive behaviors in mice

Y Zhang, Y Wei, T Zheng, Y Tao, Y Sun, D Jiang… - The Journal of …, 2023 - Springer
Background Adipokines, including adiponectin, are implicated in nociceptive pain; however,
the underlying cellular and molecular mechanisms remain unknown. Methods Using …

Adiponectin action: a combination of endocrine and autocrine/paracrine effects

K Dadson, Y Liu, G Sweeney - Frontiers in endocrinology, 2011 - frontiersin.org
The widespread physiological actions of adiponectin have now been well characterized as
clinical studies and works in animal models have established strong correlations between …

Adiponectin regulates bone marrow mesenchymal stem cell niche through a unique signal transduction pathway: an approach for treating bone disease in diabetes

L Yu, Q Tu, Q Han, L Zhang, L Sui, L Zheng, S Meng… - Stem …, 2015 - academic.oup.com
Adiponectin (APN) is an adipocyte-secreted adipokine that exerts well-characterized
antidiabetic properties. Patients with type 2 diabetes (T2D) are characterized by reduced …