Substituted (E)-2-Oxo-3-butenoates: Reagents for Every Enantioselectively-Catalyzed Reaction

G Desimoni, G Faita, P Quadrelli - Chemical Reviews, 2013 - ACS Publications
In view of the importance of these molecules in the synthesis of organic compounds,
arylidene pyruvates (1, R= Ar) have been considered as worthy of a general review, starting …

Candida parapsilosis: A versatile biocatalyst for organic oxidation-reduction reactions

A Chadha, S Venkataraman, R Preetha, SK Padhi - Bioorganic chemistry, 2016 - Elsevier
This review highlights the importance of the biocatalyst, Candida parapsilosis for oxidation
and reduction reactions of organic compounds and establishes its versatility to generate a …

Asymmetric reduction of aryl imines using Candida parapsilosis ATCC 7330

T Vaijayanthi, A Chadha - Tetrahedron: Asymmetry, 2008 - Elsevier
A highly enantioselective one pot, novel biocatalytic method for the asymmetric reduction of
aryl imines is reported. Treatment of aryl imines with Candida parapsilosis ATCC 7330 in …

Regio- and Stereospecific C- and O-Allylation of Phenols via π-Allyl Pd Complexes Derived from Allylic Ester Carbonates

CA Discolo, AG Graves… - The Journal of Organic …, 2017 - ACS Publications
Two complementary strategies have been developed for the C-and O-allylation of phenols
via a common π-allyl Pd complex. While O-allylation of phenols by this method is a well …

Deracemisation of aryl substituted α-hydroxy esters using Candida parapsilosis ATCC 7330: effect of substrate structure and mechanism

B Baskar, NG Pandian, K Priya, A Chadha - Tetrahedron, 2005 - Elsevier
Candida parapsilosis ATCC 7330 was found to be an efficient biocatalyst for the
deracemisation of aryl α-hydroxy esters (65–85% yield and 90–99% ee). A variety of aryl …

One-pot synthesis of enantiomerically pure 1, 2-diols: asymmetric reduction of aromatic α-oxoaldehydes catalysed by Candida parapsilosis ATCC 7330

P Mahajabeen, A Chadha - Tetrahedron: Asymmetry, 2011 - Elsevier
A facile and simple one-pot method was developed to produce a series of optically active (S)-
1-phenyl-1, 2-ethanediols with good yields (up to 70%) and high enantiomeric excess (> …

(S)-specific carbonyl reductase from Candida parapsilosis ATCC 7330 as a model for the initial screening of inhibitors for human carbonyl reductase

K Leena, SN Gummadi, A Chadha - Biochemical Engineering Journal, 2024 - Elsevier
Human carbonyl reductase (CBR1) reduces carbonyl groups in drug molecules, particularly
anticancer drugs, leading to altered pharmacological effects. This study reports a simple and …

Candida spp. redox machineries: An ample biocatalytic platform for practical applications and academic insights

D Gamenara, PD de María - Biotechnology advances, 2009 - Elsevier
The use of oxidoreductases as biocatalysts for the production of a wide number of chiral
building blocks is presently a mature (bio-) technology. In this context some industrial …

Transition‐Metal‐Free Reduction of α‐Keto Thioesters with Hydrosilanes at Room Temperature: Divergent Synthesis through Reagent‐Controlled Chemoselectivities

R Maity, B Das, I Das - Advanced Synthesis & Catalysis, 2019 - Wiley Online Library
The combination of hydrosilanes with a Brønsted or Lewis acid as a promoter can be used
for the reagent‐controlled chemoselective reduction at room temperature of conjugated C …

A carbonyl reductase from Candida parapsilosis ATCC 7330: substrate selectivity and enantiospecificity

S Sudhakara, A Chadha - Organic & Biomolecular Chemistry, 2017 - pubs.rsc.org
Candida parapsilosis ATCC 7330, a rich source of highly stereospecific oxidoreductases,
catalyzes oxidation–reduction of a plethora of compounds yielding industrially important …