Systems and synthetic biology tools for advanced bioproduction hosts

Y Chen, D Banerjee, A Mukhopadhyay… - Current opinion in …, 2020 - Elsevier
The genomic revolution ushered in an era of discovery and characterization of enzymes
from novel organisms that fueled engineering of microbes to produce commodity and high …

Isotope-assisted metabolic flux analysis: a powerful technique to gain new insights into the human metabolome in health and disease

B Moiz, A Li, S Padmanabhan, G Sriram, AM Clyne - Metabolites, 2022 - mdpi.com
Cell metabolism represents the coordinated changes in genes, proteins, and metabolites
that occur in health and disease. The metabolic fluxome, which includes both intracellular …

BayFlux: A Bayesian method to quantify metabolic Fluxes and their uncertainty at the genome scale

TWH Backman, C Schenk, T Radivojevic… - PLoS computational …, 2023 - journals.plos.org
Metabolic fluxes, the number of metabolites traversing each biochemical reaction in a cell
per unit time, are crucial for assessing and understanding cell function. 13C Metabolic Flux …

Global connectivity in genome-scale metabolic networks revealed by comprehensive FBA-based pathway analysis

Y Gao, Q Yuan, Z Mao, H Liu, H Ma - BMC microbiology, 2021 - Springer
Background Graph-based analysis (GBA) of genome-scale metabolic networks has
revealed system-level structures such as the bow-tie connectivity that describes the overall …

Strategies to improve microbial lipid production: Optimization techniques

D Mahajan, S Sengupta, S Sen - Biocatalysis and Agricultural …, 2019 - Elsevier
The exponentially depleting fossil fuel reserves has led to the growth of lipids being used as
an alternate potential feedstock, derived from varied sources, including plants, animals and …

[图书][B] Engineering Yeast for Improved Recombinant Protein Production

Y Wang - 2023 - search.proquest.com
Recombinant proteins are broadly used from basic research to therapeutic development and
include industrial enzymes and pharmaceutical proteins. The increasing demand for …