Clinical features, immunopathogenesis, and therapeutic strategies in vitiligo

Y Wang, S Li, C Li - Clinical Reviews in Allergy & Immunology, 2021 - Springer
Vitiligo is an autoimmune disease of the skin characterized by epidermal melanocyte loss
resulting in white patches, with an approximate prevalence of 0.5–2% worldwide. Several …

Viral manipulation of host cell necroptosis and pyroptosis

S Verdonck, J Nemegeer, P Vandenabeele… - Trends in …, 2022 - cell.com
Cell death forms an essential component of the antiviral immune response. Viral infection
elicits different forms of host cell death, including the lytic and inflammatory cell death modes …

Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

S Flommersfeld, JP Böttcher, J Ersching, M Flossdorf… - Immunity, 2021 - cell.com
Upon viral infection, natural killer (NK) cells expressing certain germline-encoded receptors
are selected, expanded, and maintained in an adaptive-like manner. Currently, these are …

Human cytomegalovirus in cancer: the mechanism of HCMV-induced carcinogenesis and its therapeutic potential

C Yu, S He, W Zhu, P Ru, X Ge… - Frontiers in Cellular and …, 2023 - frontiersin.org
Cancer is one of the leading causes of death worldwide. Human cytomegalovirus (HCMV), a
well-studied herpesvirus, has been implicated in malignancies derived from breast …

Cell-type apoptosis in lung during SARS-CoV-2 infection

Y Liu, TM Garron, Q Chang, Z Su, C Zhou, Y Qiu… - Pathogens, 2021 - mdpi.com
The SARS-CoV-2 pandemic has inspired renewed interest in understanding the
fundamental pathology of acute respiratory distress syndrome (ARDS) following infection …

[HTML][HTML] Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy

TR Müller, S Jarosch, M Hammel, J Leube… - Cell Reports …, 2021 - cell.com
Adoptive transfer of T cells expressing a transgenic T cell receptor (TCR) has the potential to
revolutionize immunotherapy of infectious diseases and cancer. However, the generation of …

A cytomegalovirus inflammasome inhibitor reduces proinflammatory cytokine release and pyroptosis

Y Deng, E Ostermann, W Brune - Nature communications, 2024 - nature.com
In response to viral infection, cells can initiate programmed cell death (PCD), leading to a
reduction in the release of viral progeny. Viruses have therefore evolved specific …

Human motor neurons derived from induced pluripotent stem cells are susceptible to SARS-CoV-2 infection

G Cappelletti, C Colombrita, F Limanaqi… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction COVID-19 typically causes Q7 respiratory disorders, but a high proportion of
patients also reports neurological and neuromuscular symptoms during and after SARSCoV …

Differential effects of CMV infection on the viability of cardiac cells

SK Yadav, FI Gawargi, MH Hasan, R Tandon… - Cell Death …, 2023 - nature.com
Cytomegalovirus (CMV) is a widely prevalent herpesvirus that reaches seroprevalence rates
of up to 95% in several parts of the world. The majority of CMV infections are asymptomatic …

Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells

S Ebert, V Böhm, JK Büttner, W Brune… - Plos …, 2024 - journals.plos.org
CD8 T cells are the predominant effector cells of adaptive immunity in preventing
cytomegalovirus (CMV) multiple-organ disease caused by cytopathogenic tissue infection …