RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …

RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …

Although microRNAs (miRNAs), other non-coding RNAs (ncRNAs)(eg lncRNAs,
pseudogenes and circRNAs) and competing endogenous RNAs (ceRNAs) have been …

RNA binding proteins (RBPs) regulate all aspects in the life cycle of RNA molecules. To
elucidate the elements that guide RNA specificity, regulatory mechanisms, and functions of …

Background Long noncoding RNAs (lncRNAs) are a recently discovered class of non-
protein coding RNAs, which have now increasingly been shown to be involved in a wide …

High-throughput experimental technologies are generating increasingly massive and
complex genomic data sets. The sheer enormity and heterogeneity of these data threaten to …

To exert regulatory function, miRNAs guide Argonaute (AGO) proteins to partially
complementary sites on target RNAs. Crosslinking and immunoprecipitation (CLIP) assays …

Post-transcriptional gene regulation (PTGR) of mRNA turnover, localization and translation
is mediated by microRNAs (miRNAs) and RNA-binding proteins (RBPs). These regulators …

From transcriptional noise to dark matter of biology, the rapidly changing view of long non-
coding RNA (lncRNA) leads to deep understanding of human complex diseases induced by …

Owing to their preeminent biological functions, the repertoire of expressed RNA-binding
proteins (RBPs) and their activity states are highly informative about cellular systems. We …