Monoclonal antibodies (mAbs) have become one of the most important classes of
biopharmaceutical products, and they continue to dominate the universe of …

Simple Summary Monoclonal antibodies are increasingly used for a broad range of
diseases. Rising demand must face with time time-consuming and laborious processes to …

B7-H3 (CD276) has emerged as a target for cancer immunotherapy by virtue of consistent
expression in many malignancies, relative absence from healthy tissues, and an emerging …

Deep parallel sequencing (NGS) is a viable tool for monitoring scFv and Fab library
dynamics in many antibody engineering high-throughput screening efforts. Although very …

Laser-assisted recovery of on-chip phage viral DNA was demonstrated. Optomechanical
energy conversion was utilized to shear off a part of a microchip and thereby form a …

Bacteriophages infect and replicate within bacteria and play a key role in the environment,
particularly in microbial ecosystems and bacterial population dynamics. The increasing …

c-Met is a promising target in cancer therapy for its intrinsic oncogenic properties. However,
there are currently no c-Met-specific inhibitors available in the clinic. Antibodies blocking the …

Middle East respiratory syndrome coronavirus (MERS-CoV) induces severe aggravating
respiratory failure in infected patients, frequently resulting in mechanical ventilation. As …

Next-generation sequencing (NGS) is an indispensable tool in antibody discovery projects.
However, the limits on NGS read length make it difficult to reconstruct full antibody …

Recent advances in biochip technologies that connect next-generation sequencing (NGS) to
real-world problems have facilitated breakthroughs in science and medicine. Because …