Mechanics insights of alpha-lipoic acid against cardiovascular diseases during COVID-19 infection
L Rochette, S Ghibu - International Journal of Molecular Sciences, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China, in late December
2019. Since then, COVID-19 has spread rapidly worldwide and was declared a global …
2019. Since then, COVID-19 has spread rapidly worldwide and was declared a global …
Associations of oxidative stress and postoperative outcome in liver surgery with an outlook to future potential therapeutic options
T Senoner, S Schindler, S Stättner… - Oxidative Medicine …, 2019 - Wiley Online Library
Several types of surgical procedures have shown to elicit an inflammatory stress response,
leading to substantial cytokine production and formation of oxygen‐based or nitrogen …
leading to substantial cytokine production and formation of oxygen‐based or nitrogen …
[HTML][HTML] Phoenix dactylifera protects against oxidative stress and hepatic injury induced by paracetamol intoxication in rats
The current studies were sought to determine effects of antioxidant potential of aqueous and
methanolic extracts of Phoenix dactylifera leaves (PLAE and PLME) against the widely-used …
methanolic extracts of Phoenix dactylifera leaves (PLAE and PLME) against the widely-used …
α-Lipoic acid protects against cyclosporine a-induced hepatic toxicity in rats: effect on oxidative stress, inflammation, and apoptosis
EM El-Mancy, DMA Elsherbini, RH Al-Serwi… - Toxics, 2022 - mdpi.com
The clinical application of cyclosporine A (CsA) as an immunosuppressive agent is limited
by its organ toxicity. We aimed to evaluate the effectiveness of α-lipoic acid against CsA …
by its organ toxicity. We aimed to evaluate the effectiveness of α-lipoic acid against CsA …
Metabolic, immunologic, and histopathologic responses on premetamorphic American bullfrog (Lithobates catesbeianus) following exposure to lithium and selenium
FA Pinto-Vidal, C dos Santos Carvalho… - Environmental …, 2021 - Elsevier
The presence of chemicals and the destruction of freshwater habitats have been addressed
as one of the reasons for the decline in the amphibians' populations worldwide. Considering …
as one of the reasons for the decline in the amphibians' populations worldwide. Considering …
[HTML][HTML] Involvement of Nrf2, JAK and COX pathways in acetaminophen-induced nephropathy: Role of some antioxidants
QH Alqahtani, LM Fadda, AM Alhusaini… - Saudi Pharmaceutical …, 2023 - Elsevier
Objectives Acetaminophen (APAP)-induced nephrotoxicity is detrimental consequence for
which there has not been a standardized therapeutic regimen. Although, N-acetylcysteine …
which there has not been a standardized therapeutic regimen. Although, N-acetylcysteine …
α‑lipoic acid protects against carbon tetrachloride‑induced liver cirrhosis through the suppression of the TGF‑β/Smad3 pathway and autophagy
G Liu, J Liu, L Pian, S Gui, B Lu - Molecular Medicine …, 2019 - spandidos-publications.com
Abstract α‑lipoic acid (ALA) is a naturally occurring antioxidant with protective effects against
various hepatic injuries. The aim of the present study was to investigate the mechanisms by …
various hepatic injuries. The aim of the present study was to investigate the mechanisms by …
[HTML][HTML] Glycosphingolipids prevent APAP and HMG-CoA reductase inhibitors-mediated liver damage: a novel method for “safer drug” formulation that prevents drug …
Abstract Background and Aims: Acetaminophen (APAP) and HMG-CoA reductase inhibitors
are common causes of drug-induced liver injury (DILI). This study aimed to determine the …
are common causes of drug-induced liver injury (DILI). This study aimed to determine the …
Identification of acetaminophen adducts of rat liver microsomal proteins using 2D-LC-MS/MS
Xenobiotic metabolism in the liver can give rise to reactive metabolites that covalently bind
to proteins, and determining which proteins are targeted is important in drug discovery and …
to proteins, and determining which proteins are targeted is important in drug discovery and …
[HTML][HTML] The effect of acetyl-L-carnitine, alpha-lipoic acid, and coenzyme Q10 combination in preventing anti-tuberculosis drug-induced hepatotoxicity: a randomized …
R Hakimizad, R Soltani, F Khorvash… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Drug-induced liver injury (DILI) is one of the most serious adverse effects of anti-tuberculosis
(TB) drugs. A suggested mechanism of this adverse effect is mitochondrial dysfunction …
(TB) drugs. A suggested mechanism of this adverse effect is mitochondrial dysfunction …