Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …

Multiple Sclerosis (MS) is an immune-mediated neurological disorder, characterized by
central nervous system (CNS) inflammation, oligodendrocyte loss, demyelination, and …

Objective Preterm brain injury is a major cause of disability in later life, and may result in
motor, cognitive and behavioural impairment for which no treatment is currently available …

Traumatic brain injury (TBI) is distinct from other neurological disorders because it is
induced by a discrete event that applies extreme mechanical forces to the brain. This review …

Central nervous system (CNS) lesions are major causes of human death and disability
worldwide, and they cause different extents of motor and sensory dysfunction in patients …

In diseases such as multiple sclerosis (MS), inflammation can injure the myelin sheath that
surrounds axons, a process known as demyelination. The spontaneous regeneration of …

Traumatic brain injury (TBI) patients often exhibit slowed information processing speed that
can underlie diverse symptoms. Processing speed depends on neural circuit function at …

A major consequence of traumatic brain and spinal cord injury is the loss of the myelin
sheath, a cholesterol-rich layer of insulation that wraps around axons of the nervous system …

Traumatic brain injury (TBI) is one of the most common causes of neurological damage in
young human populations. Vitamin B12 has been reported to promote axon growth of …

Multiple sclerosis (MS) is an inflammatory disease characterized by myelin loss. While
therapies exist to slow MS progression, no treatment currently exists for remyelination …