Efficacy and Mechanisms of Aerobic Exercise on Cancer Initiation, Progression, and Metastasis: A Critical Systematic Review of In Vivo Preclinical Data

KA Ashcraft, RM Peace, AS Betof, MW Dewhirst… - Cancer research, 2016 - AACR
A major objective of the emerging field of exercise–oncology research is to determine the
efficacy of, and biological mechanisms by which, aerobic exercise affects cancer incidence …

Exercise as adjunct therapy in cancer

KA Ashcraft, AB Warner, LW Jones… - Seminars in radiation …, 2019 - Elsevier
Data from observational studies indicate that both physical activity as well as exercise (ie,
structured physical activity) is associated with reductions in the risk of recurrence and cancer …

[HTML][HTML] MicroRNAs as important regulators of exercise adaptation

GJJ Silva, A Bye, H El Azzouzi, U Wisløff - Progress in cardiovascular …, 2017 - Elsevier
A significant body of evidence supports the protective role of exercise training (ET) in
cardiovascular diseases, skeletal muscle dystrophies, several types of cancer, Alzheimer …

Reframing how physical activity reduces the incidence of clinically-diagnosed cancers: appraising exercise-induced immuno-modulation as an integral mechanism

A Emery, S Moore, JE Turner, JP Campbell - Frontiers in Oncology, 2022 - frontiersin.org
Undertaking a high volume of physical activity is associated with reduced risk of a broad
range of clinically diagnosed cancers. These findings, which imply that physical activity …

Physical activity and cancer prevention: pathways and targets for intervention

CJ Rogers, LH Colbert, JW Greiner, SN Perkins… - Sports Medicine, 2008 - Springer
The prevalence of obesity, an established epidemiological risk factor for many cancers, has
risen steadily for the past several decades in the US and many other countries. Particularly …

Physical exercise, health, and disease treatment: The role of macrophages

IOM Callegari, GZ Rocha, AG Oliveira - Frontiers in Physiology, 2023 - frontiersin.org
Subclinical inflammation is linked to comorbidities and risk factors, consolidating the
diagnosis of chronic non-communicable diseases, such as insulin resistance …

The effect of exercise on IL-6-induced cachexia in the Apc Min/+ mouse

MJ Puppa, JP White, KT Velázquez… - Journal of cachexia …, 2012 - Springer
Background Cachexia involves unintentional body weight loss including diminished muscle
and adipose tissue mass and is associated with an underlying disease. Systemic …

[HTML][HTML] Resistance exercise modulates lipid plasma profile and cytokine content in the adipose tissue of tumour-bearing rats

FF Donatto, RX Neves, FO Rosa, RG Camargo… - Cytokine, 2013 - Elsevier
Cancer cachexia is a multifactorial syndrome characterised by progressive weight loss,
frequently accompanied by anorexia, sarcopenia, and chronic systemic inflammation. The …

Can exercise-induced modulation of the tumor physiologic microenvironment improve antitumor immunity?

X Zhang, KA Ashcraft, A Betof Warner, SK Nair… - Cancer research, 2019 - AACR
The immune system plays an important role in controlling cancer growth. However, cancers
evolve to evade immune detection. Immune tolerance and active immune suppression …

Endurance training induces depot-specific changes in IL-10/TNF-α ratio in rat adipose tissue

FS Lira, JC Rosa, AS Yamashita, CH Koyama… - Cytokine, 2009 - Elsevier
White adipose tissue (WAT) is the source of pro-and anti-inflammatory cytokines and
recently, it has been recognized as an important source of interleukin 10 (IL-10). Acute …