As ultraprocessed foods (ie, foods composed of mostly cheap industrial sources of dietary
energy and nutrients plus additives) have become more abundant in our food supply, rates …

Abstract Naloxone is a World Health Organization (WHO)-listed essential medicine and is
the first choice for treating the respiratory depression of opioids, also by lay-people …

To identify signaling pathways activated by oxycodone self-administration (SA), Sprague–
Dawley rats self-administered oxycodone for 20 days using short—(ShA, 3 h) and long …

Fentanyl is a synthetic opioid widely used for its potent analgesic effects in chronic pain
management and intraoperative anesthesia. However, its high potency, low cost, and …

Background Oxycodone is a commonly used oral opioid in children for treating
postoperative pain. Highly polymorphic gene CYP2D6 metabolizes oxycodone into its more …

The misuse and abuse of opioid analgesics continue to pose a serious public health
concern, but for some patients, opioids remain an important analgesic option. Extended …

Rationale It is unclear if e-cigarettes have reduced abuse liability relative to traditional
cigarettes, especially when considering advanced devices which deliver nicotine more …

Rationale Opioid injection drug use (IDU) has been linked to a more severe pattern of use
(eg tolerance, overdose risk) and shorter retention in treatment, which may undermine …

We recently reported an economic choice task in which squirrel monkeys chose between
differing amounts of remifentanil, a fast-acting opioid, or a food reward to develop a …

The growing issues with prescription drug misuse have required the development of
advanced techniques like abuse-deterrent formulations (ADFs). In this abstract we have …