Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications

LCC Lee, KKW Lo - Journal of the American Chemical Society, 2022 - ACS Publications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …

A carbonic anhydrase IX (CAIX)‐anchored rhenium (I) photosensitizer evokes pyroptosis for enhanced anti‐tumor immunity

X Su, WJ Wang, Q Cao, H Zhang, B Liu… - Angewandte Chemie …, 2022 - Wiley Online Library
An ideal cancer treatment should not only destroy primary tumors but also improve the
immunogenicity of the tumor microenvironment to achieve a satisfactory anti‐tumor immune …

What blocks more anticancer platinum complexes from experiment to clinic: Major problems and potential strategies from drug design perspectives

K Peng, BB Liang, W Liu, ZW Mao - Coordination Chemistry Reviews, 2021 - Elsevier
Encouraged by the worldwide success of cisplatin in the field of cancer chemotherapy,
intensive works have been conducted to explore more platinum coordination complexes as …

Simultaneous Photoactivation of cGAS‐STING Pathway and Pyroptosis by Platinum (II) Triphenylamine Complexes for Cancer Immunotherapy

YY Ling, XY Xia, L Hao, WJ Wang, H Zhang… - Angewandte …, 2022 - Wiley Online Library
Activation of the cyclic GMP‐AMP synthase‐stimulator of the interferon gene (cGAS‐STING)
pathway is a potent anticancer immunotherapeutic strategy, and the induction of pyroptosis …

Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells

H Fang, S Geng, M Hao, Q Chen, M Liu, C Liu… - Nature …, 2021 - nature.com
Zn2+ plays important roles in metabolism and signaling regulation. Subcellular Zn2+
compartmentalization is essential for organelle functions and cell biology, but there is …

Advanced imaging techniques for tracking drug dynamics at the subcellular level

C Zhang, Z Tian, R Chen, F Rowan, K Qiu… - Advanced Drug Delivery …, 2023 - Elsevier
Optical microscopes are an important imaging tool that have effectively advanced the
development of modern biomedicine. In recent years, super-resolution microscopy (SRM) …

Organic‐Platinum Hybrids for Covalent Binding of G‐Quadruplexes: Structural Basis and Application to Cancer Immunotherapy

LY Liu, TZ Ma, YL Zeng, W Liu… - Angewandte Chemie …, 2023 - Wiley Online Library
Abstract G‐quadruplexes (G4s) have been revived as promising therapeutic targets with the
development of immunotherapy, but the G4‐mediated immune response remains unclear …

Seeing the unseen: AIE luminogens for super-resolution imaging

Z Wang, Y Zhou, R Xu, Y Xu, D Dang, Q Shen… - Coordination Chemistry …, 2022 - Elsevier
Super-resolution imaging (SRI) is of great significance to break the Abbe's diffraction limit,
enabling visualization and dynamic monitoring with ultra-high resolution in both material …

Recent progress in metal-based molecular probes for optical bioimaging and biosensing

Y Ning, GQ Jin, MX Wang, S Gao, JL Zhang - Current Opinion in Chemical …, 2022 - Elsevier
Biological imaging and biosensing from subcellular/cellular level to whole body have
enabled non-invasive visualisation of molecular events during various biological and …