Poly (2-oxazoline) s based biomaterials: A comprehensive and critical update

T Lorson, MM Luebtow, E Wegener, MS Haider… - Biomaterials, 2018 - Elsevier
Abstract Poly (2-oxazoline) s have been investigated for decades as biomaterials.
Pioneering early work suggested that hydrophilic poly (2-oxazoline) s are comparable to …

Pharmapolymers in the 21st century: Synthetic polymers in drug delivery applications

C Englert, JC Brendel, TC Majdanski, T Yildirim… - Progress in Polymer …, 2018 - Elsevier
The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …

Antibiofouling polymer interfaces: poly (ethylene glycol) and other promising candidates

S Lowe, NM O'Brien-Simpson, LA Connal - Polymer Chemistry, 2015 - pubs.rsc.org
Nonspecific protein adsorption and/or microbial adsorption on biomedical materials
adversely affects the efficacy of a range of biomedical systems, from implants and …

25th anniversary article: designer hydrogels for cell cultures: a materials selection guide

J Thiele, Y Ma, SMC Bruekers, S Ma… - Advanced …, 2014 - Wiley Online Library
Cell culturing, whether for tissue engineering or cell biology studies, always involves placing
cells in a non‐natural environment and no material currently exist that can mimic the entire …

Recent advances in stealth coating of nanoparticle drug delivery systems

Z Amoozgar, Y Yeo - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
Modifying surfaces of nanoparticles (NPs) with polyethylene glycol (PEG), the so‐called
PEGylation, is the most commonly used method for reducing premature clearance of NPs …

Poly (2‐oxazoline) s as Polymer Therapeutics

R Luxenhofer, Y Han, A Schulz, J Tong… - Macromolecular …, 2012 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (POx) are currently discussed as an upcoming polymer
platform for biomaterials design and especially for polymer therapeutics. POx meet specific …

Temperature responsive bio-compatible polymers based on poly (ethylene oxide) and poly (2-oxazoline) s

C Weber, R Hoogenboom, US Schubert - Progress in Polymer Science, 2012 - Elsevier
This review covers the LCST behavior of two important polymer classes in aqueous solution,
namely poly (2-oxazoline) s and systems whose thermo-responsiveness is based on their …

Poly (2‐Oxazoline) s–Are They More Advantageous for Biomedical Applications Than Other Polymers?

O Sedlacek, BD Monnery, SK Filippov… - Macromolecular …, 2012 - Wiley Online Library
Abstract Poly (2‐alkyl‐2‐oxazoline) s are biocompatible polymers with polypeptide‐isomeric
structures that are attracting increasing interest as biomaterials for drug, gene, protein, and …

Poly (2‐ethyl‐2‐oxazoline) as Alternative for the Stealth Polymer Poly (ethylene glycol): Comparison of in vitro Cytotoxicity and Hemocompatibility

M Bauer, C Lautenschlaeger, K Kempe… - Macromolecular …, 2012 - Wiley Online Library
Limitations of PEG in drug delivery have been reported from clinical trials. PEtOx (0.4–40
kDa) as alternative is synthesized by a living, microwave‐assisted polymerization, and is …

Polyoxazolines for nonfouling surface coatings—a direct comparison to the gold standard PEG

R Konradi, C Acikgoz, M Textor - Macromolecular rapid …, 2012 - Wiley Online Library
The prevention of surface fouling is becoming increasingly important for the development of
anti‐infective medical implants, biosensors with improved signal‐to‐noise ratios, and low …