Breast cancer (BC) as one of the most common causes of human deaths among women, is
always considered one of the global health challenges. Despite various advances in …

Multiple studies have confirmed that speckle-type pox virus and zinc finger (POZ) protein
(SPOP) functions as a substrate adaptor of cullin 3-based E3 ligase and has a crucial role in …

The long non-coding RNA (lncRNA) HOXA cluster antisense RNA2 (HOXA-AS2) has
recently been shown to be dysregulated and involved in the progression of several cancers …

Long, noncoding RNAs (lncRNAs) are indispensable for normal cell physiology and,
consequently, are tightly regulated in human cells. Yet, unlike mRNA, substantially less is …

Understanding the mechanisms underlying abnormal egg production and pregnancy loss is
significant for human fertility. SENP7, a SUMO poly-chain editing enzyme, has been …

Chromobox (CBX) proteins are important epigenetic regulatory proteins and are widely
involved in biological processes, such as embryonic development, the maintenance of stem …

SUMO post-translational modification of proteins or SUMOylation ensures normal cell
function. Disruption of SUMO dynamics prompts various pathophysiological conditions …

More and more researches have shown the vital functions of long non-coding RNAs
(LncRNAs) in modulating the biological progresses in tumorigenesis. OR3A4 is such a type …

Plants regularly encounter various environmental stresses such as salt, drought, cold, heat,
heavy metals and pathogens, leading to changes in their proteome. Of these, a post …

Breast cancer has the highest incidence among cancers and is the most frequent cause of
death in women worldwide. The detailed mechanism of the pathogenesis of breast cancer …