Dynamics of biomarkers in relation to aging and mortality

KG Arbeev, SV Ukraintseva, AI Yashin - Mechanisms of ageing and …, 2016 - Elsevier
Contemporary longitudinal studies collect repeated measurements of biomarkers allowing
one to analyze their dynamics in relation to mortality, morbidity, or other health-related …

The quadratic hazard model for analyzing longitudinal data on aging, health, and the life span

AI Yashin, KG Arbeev, I Akushevich, A Kulminski… - Physics of Life …, 2012 - Elsevier
A better understanding of processes and mechanisms linking human aging with changes in
health status and survival requires methods capable of analyzing new data that take into …

Age trajectories of physiological indices in relation to healthy life course

KG Arbeev, SV Ukraintseva, I Akushevich… - Mechanisms of Ageing …, 2011 - Elsevier
We analysed relationship between the risk of onset of “unhealthy life”(defined as the onset of
cancer, cardiovascular diseases, or diabetes) and longitudinal changes in body mass index …

On the immortal hydra. Again

AN Khokhlov - Moscow University Biological Sciences Bulletin, 2014 - Springer
The long history of ideas about the most famous “immortal”(non-aging) organism, freshwater
hydra, is shortly reviewed. Over the years this polyp has attracted the attention of naturalists …

Optimal versus realized trajectories of physiological dysregulation in aging and their relation to sex-specific mortality risk

KG Arbeev, AA Cohen, LS Arbeeva, E Milot… - Frontiers in Public …, 2016 - frontiersin.org
While longitudinal changes in biomarker levels and their impact on health have been
characterized for individual markers, little is known about how overall marker profiles may …

How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity

AI Yashin, KG Arbeev, LS Arbeeva, D Wu, I Akushevich… - Biogerontology, 2016 - Springer
Increasing proportions of elderly individuals in developed countries combined with
substantial increases in related medical expenditures make the improvement of the health of …

How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data

AI Yashin, KG Arbeev, D Wu, LS Arbeeva… - Frontiers in …, 2013 - frontiersin.org
Background and Objective: The influence of genes on human lifespan is mediated by
biological processes that characterize body's functioning. The age trajectories of these …

Filtered likelihood for point processes

K Giesecke, G Schwenkler - Journal of Econometrics, 2018 - Elsevier
Point processes are widely used in finance and economics to model the timing of defaults,
market transactions, unemployment spells, births, and a range of other events. We develop …

[图书][B] Biodemography of aging: Determinants of healthy life span and longevity

AI Yashin, E Stallard, KC Land - 2016 - books.google.com
This volume is a critical exposition of the data and analyses from a full decade of rigorous
research into how age-related changes at the individual level, along with other factors …

Joint analyses of longitudinal and time-to-event data in research on aging: Implications for predicting health and survival

KG Arbeev, I Akushevich, AM Kulminski… - Frontiers in public …, 2014 - frontiersin.org
Longitudinal data on aging, health, and longevity provide a wealth of information to
investigate different aspects of the processes of aging and development of diseases leading …