Inflammasomes are multi-protein complexes composed of a NOD-like receptor (NLR)/an
AIM-like receptor (ALR), the adapter molecule apoptosis-associated speck-like protein that …

Autoimmune hepatitis (AIH) fulfills the generally accepted contemporary criteria of an
autoimmune liver disease: the presence of autoantibodies and autoreactive T cells, a female …

Objective A close relationship between gut microbiota and some chronic liver disorders has
recently been described. Herein, we systematically performed a comparative analysis of the …

Primary biliary cholangitis (PBC) has been regarded as female-predominant without
evidence of gender difference in survival. We aimed to compare the overall survival …

Primary biliary cirrhosis (PBC) is a chronic cholestatic immune liver disease characterized
by persistent cholestasis, interlobular bile duct damage, portal inflammation, liver fibrosis …

Autoimmune hepatitis (AIH) is a severe and chronic liver disease, and its incidence has
increased worldwide in recent years. Research into the pathogenesis of AIH remains limited …

The anatomical architecture of the human liver and the diversity of its immune components
endow the liver with its physiological function of immune competence. Adaptive immunity is …

Regulatory T-cells (Tregs) are key players in the maintenance of immune homeostasis by
preventing immune responses to self-antigens. Defects in Treg frequency and/or function …

The aryl hydrocarbon receptor (AHR) is a ubiquitously expressed ligand-activated
transcription factor with multifaceted physiological functions. In the immune system, AHR has …

We have focused on the epidemiology and immunobiology of Zika virus (ZIKV) infection and
factors associated with the development of Guillain-Barré syndrome (GBS) and other …