Use of hypertonic saline solutions in treatment of cerebral... : Critical Care Medicine Use of
hypertonic saline solutions in treatment of cerebral edema and intracranial hypertension …

Abstract THERE IS NO question that substantial progress has been made over the last 30
years, since the pioneering multinational studies of Jennett and colleagues, in our …

Background Induction of hypothermia in patients with brain injury was shown to improve
outcomes in small clinical studies, but the results were not definitive. To study this issue, we …

Object. The criteria for the use of mild hypothermia (34° C) in severely head injured patients
have not been standardized. A prospective randomized controlled trial was conducted to …

Delayed but prolonged hypothermia persistently decreases cell death and functional deficits
after global cerebral ischemia in rodents. Postischemic hypothermia also reduces infarction …

Moderate hypothermia delays proinflammatory cytokine product... : Critical Care Medicine
Moderate hypothermia delays proinflammatory cytokine production of human peripheral blood …

OBJECTIVE: We studied the effect of hypothermia on intracranial pressure, systemic and
intracranial hemodynamics, and metabolism in patients with severe traumatic brain injury to …

BACKGROUND: The therapeutic mechanism and clinical effect of mild hypothermia in
patients with severe head injury were studied. METHODS: All 396 patients with severe head …

BACKGROUND Traumatic brain injury (TBI) is a major cause of disability and death in
young adults worldwide. It results in around 1 million hospital admissions annually in the …

Increased intracranial pressure (ICP) is a pathologic state common to a variety of serious
neurologic conditions, all of which are characterized by the addition of volume to the …