There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …

In this review, the history of boron's early use in drugs, and the history of the use of boron
functional groups in medicinal chemistry applications are discussed. This includes …

The membrane translocation of hydrophilic substances constitutes a challenge for their
application as therapeutic compounds and labelling probes,,–. To remedy this, charged …

Boron compounds now have many applications in a number of fields, including Medicinal
Chemistry. Although the uses of boron compounds in pharmacological science have been …

o-C2B10H12 isomerizes to m-C2B10H12 upon heating at 400° C. Deboronation in o-
C2B10H12 is a relatively easy process, whereas it is more difficult in m-C2B10H12. These …

A standard goal of medicinal chemists has been to discover efficient and potent drug
candidates with specific enzyme-inhibitor abilities. In this regard, boron-based bioactive …

Amination of carboranes has a good application prospect in organic and pharmaceutical
synthesis. However, the current methods used for this transformation suffer from limitations …

Aromatic polycyclic systems have been extensively utilized as structural subunits for the
preparation of various functional molecules. Currently, aromatics-based polycyclic systems …

Herein, we present a chemically robust and efficient synthesis route for B (9)-OH-o-
carboranes by the oxidation of o-carboranes with commercially available 68% HNO3 under …

Cobalt bisdicarbollides (COSANs) are inorganic boron-based anions that have been
previously reported to permeate by themselves through lipid bilayer membranes, a …