Inhaled nitric oxide in acute respiratory distress syndrome subsets: rationale and clinical applications

S Redaelli, M Pozzi, M Giani, A Magliocca… - Journal of Aerosol …, 2023 - liebertpub.com
Acute respiratory distress syndrome (ARDS) is a life-threatening condition, characterized by
diffuse inflammatory lung injury. Since the coronavirus disease 2019 (COVID-19) pandemic …

[HTML][HTML] Detecting free radicals post viral infections

VG Damle, K Wu, DJ Arouri, R Schirhagl - Free Radical Biology and …, 2022 - Elsevier
Free radical generation plays a key role in viral infections. While free radicals have an
antimicrobial effect on bacteria or fungi, their interplay with viruses is complicated and varies …

Combining L-Arginine with vitamin C improves long-COVID symptoms: The LINCOLN Survey

R Izzo, V Trimarco, P Mone, T Aloè, MC Marzani… - Pharmacological …, 2022 - Elsevier
Introduction Recent evidence suggests that oxidative stress and endothelial dysfunction play
critical roles in the pathophysiology of COVID-19 and Long-COVID. We hypothesized that a …

A nitric oxide responsive AIE probe for detecting the progression of osteoarthritis

P Jin, G Xu, X Chen, SC Li, L Cheng, P Sui… - Journal of Materials …, 2023 - pubs.rsc.org
Nitric oxide (NO) is reported to be elevated in osteoarthritis (OA) both in vitro and in vivo and
may be adopted to develop fluorescent probes for detecting the progression of OA. Here we …

VEGFR and DPP-IV as Markers of Severe COVID-19 and Predictors of ICU Admission

E Pius-Sadowska, P Kulig, A Niedźwiedź… - International Journal of …, 2023 - mdpi.com
The pathophysiology of the severe course of COVID-19 is multifactorial and not entirely
elucidated. However, it is well known that the hyperinflammatory response and cytokine …

Cytokine-Induced iNOS in A549 Alveolar Epithelial Cells: A Potential Role in COVID-19 Lung Pathology

A Barilli, G Recchia Luciani, R Visigalli, R Sala, M Soli… - Biomedicines, 2023 - mdpi.com
Background. In COVID-19, an uncontrolled inflammatory response might worsen lung
damage, leading to acute respiratory distress syndrome (ARDS). Recent evidence points to …

Integrating system biology and intratumor gene therapy by trans-complementing the appropriate co-stimulatory molecule as payload in oncolytic herpes virus

A Finizio, P Pagano, A Napolano, G Froechlich… - Cancer Gene …, 2024 - nature.com
Abstract Systems biology has been applied at the multi-scale level within the cancer field,
improving cancer prevention, diagnosis and enabling precision medicine approaches. While …

Exploring dysregulated immune response genes and endothelial dysfunction biomarkers as predictors of severe COVID-19

FS Reis-Goes, NN Silva, TM Gondim… - International …, 2023 - Elsevier
Identifying individuals and factors associated with severe cases of COVID-19 is crucial as
the pandemic continues to spread globally. Effective biomarkers for predicting severe cases …

Arterial stiffness in adults with Long COVID in sub‐Saharan Africa

C Theresa, B Katebe, CA Shibao… - Physiological …, 2024 - Wiley Online Library
Abstract Severe acute coronavirus‐2 (SARS‐CoV‐2) infection has been associated with
endothelial damage, and impaired nitric oxide production, which results in arterial stiffness …

[HTML][HTML] Serum HDL and their subfractions are impaired in multisystem inflammatory syndrome in children (MIS-C)

A Giannattasio, A Castaldo… - Journal of …, 2025 - … -medicine.biomedcentral.com
Multisystem inflammatory syndrome in children (MIS-C) is a severe post-COVID condition
due to a delayed hyperimmune response to SARS-CoV-2. High-density lipoproteins (HDL) …