Pharmacological treatment of anxiety disorders: the role of the HPA axis

GE Tafet, CB Nemeroff - Frontiers in psychiatry, 2020 - frontiersin.org
Stress in general, and early life stress in particular, has been associated with the
development of anxiety and mood disorders. The molecular, biological and psychological …

Neuroendocrine pharmacology of stress

GA Carrasco, LD Van de Kar - European journal of pharmacology, 2003 - Elsevier
Exposure to hostile conditions initiates responses organized to enhance the probability of
survival. These coordinated responses, known as stress responses, are composed of …

Functional subsets of serotonergic neurones: implications for control of the hypothalamic‐pituitary‐adrenal axis

CA Lowry - Journal of neuroendocrinology, 2002 - Wiley Online Library
Serotonergic systems play an important role in the regulation of behavioural, autonomic and
endocrine responses to stressful stimuli. This includes modulation of both the hypothalamic …

Neural substrates linking balance control and anxiety

CD Balaban - Physiology & behavior, 2002 - Elsevier
This communication provides an update of our understanding of the neurological bases for
the close association between balance control and anxiety. New data suggest that a …

Forebrain pathways mediating stress-induced hormone secretion

LD Van de Kar, ML Blair - Frontiers in neuroendocrinology, 1999 - Elsevier
Exposure to hostile conditions initiates the secretion of several hormones, including
corticosterone/cortisol, catecholamines, prolactin, oxytocin, and renin, as part of the survival …

Anatomic and functional topography of the dorsal raphe nucleus

JK Abrams, PL Johnson, JH Hollis… - Annals of the New York …, 2004 - Wiley Online Library
Serotonergic systems play an important and generalized role in regulation of sleep‐wake
states and behavioral arousal. Recent in vivo electrophysiologic recording studies in …

Modulation of anxiety circuits by serotonergic systems

CA Lowry, PL Johnson, A Hay-Schmidt, J Mikkelsen… - Stress, 2005 - Taylor & Francis
Anxiety is a complex emotional state associated with sustained heightened autonomic and
behavioral arousal and an increase in avoidance behavior. Anxiety-related behavior is a …

Behavioral and cellular consequences of increasing serotonergic activity during brain development: a role in autism?

PM Whitaker-Azmitia - International Journal of Developmental …, 2005 - Elsevier
The hypothesis explored in this review is that the high levels of serotonin in the blood seen
in some autistic children (the so-called hyperserotonemia of autism) may lead to some of the …

Stress, arousal, and sleep

LD Sanford, D Suchecki, P Meerlo - Sleep, neuronal plasticity and brain …, 2015 - Springer
Stress is considered to be an important cause of disrupted sleep and insomnia. However,
controlled and experimental studies in rodents indicate that effects of stress on sleep–wake …

Vesicular glutamate transporter 3‐expressing nonserotonergic projection neurons constitute a subregion in the rat midbrain raphe nuclei

H Hioki, H Nakamura, YF Ma, M Konno… - Journal of …, 2010 - Wiley Online Library
We previously reported that about 80% of vesicular glutamate transporter 3 (VGLUT3)‐
positive cells displayed immunoreactivity for serotonin, but the others were negative in the …