Horizons in the evolution of aging
T Flatt, L Partridge - BMC biology, 2018 - Springer
Between the 1930s and 50s, evolutionary biologists developed a successful theory of why
organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …
organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …
Immortalizing cells for human consumption
E Soice, J Johnston - International Journal of Molecular Sciences, 2021 - mdpi.com
The need to produce immortal, food-relevant cell lines is one of the most pressing
challenges of cellular agriculture, the field which seeks to produce meat and other animal …
challenges of cellular agriculture, the field which seeks to produce meat and other animal …
Intergenerational transfer of ageing: parental age and offspring lifespan
The extent to which the age of parents at reproduction can affect offspring lifespan and other
fitness-related traits is important in our understanding of the selective forces shaping life …
fitness-related traits is important in our understanding of the selective forces shaping life …
[HTML][HTML] Aging across the tree of life: The importance of a comparative perspective for the use of animal models in aging
AA Cohen - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Use of model organisms in aging research is problematic because our ability to extrapolate
across the tree of life is not clear. On one hand, there are conserved pathways that regulate …
across the tree of life is not clear. On one hand, there are conserved pathways that regulate …
The evolution of the hallmarks of aging
M Lemoine - Frontiers in Genetics, 2021 - frontiersin.org
The evolutionary theory of aging has set the foundations for a comprehensive understanding
of aging. The biology of aging has listed and described the “hallmarks of aging,” ie, cellular …
of aging. The biology of aging has listed and described the “hallmarks of aging,” ie, cellular …
Comparative transcriptomic analysis of the mechanisms underpinning ageing and fecundity in social insects
J Korb, K Meusemann, D Aumer… - … of the Royal …, 2021 - royalsocietypublishing.org
The exceptional longevity of social insect queens despite their lifelong high fecundity
remains poorly understood in ageing biology. To gain insights into the mechanisms that …
remains poorly understood in ageing biology. To gain insights into the mechanisms that …
A unified framework for evolutionary genetic and physiological theories of aging
Why and how we age are 2 intertwined questions that have fascinated scientists for many
decades. However, attempts to answer these questions remain compartmentalized …
decades. However, attempts to answer these questions remain compartmentalized …
An integrative view of senescence in nature
JM Gaillard, JF Lemaître - Functional Ecology, 2020 - Wiley Online Library
Senescence—the decline in age‐specific contribution to fitness with increasing age—has
been widely investigated in evolutionary ecology. A tremendous amount of detailed …
been widely investigated in evolutionary ecology. A tremendous amount of detailed …
[HTML][HTML] What if there's no such thing as “aging”?
Are diseases caused by aging? What are the mechanisms of aging? Do all species age?
These hotly debated questions revolve around a unitary definition of aging. Because we use …
These hotly debated questions revolve around a unitary definition of aging. Because we use …
Delivering the promises of trait‐based approaches to the needs of demographic approaches, and vice versa
Few facets of biology vary more than functional traits and life‐history traits. To explore this
vast variation, functional ecologists and population ecologists have developed independent …
vast variation, functional ecologists and population ecologists have developed independent …