The role of magnesium in neurological disorders

AE Kirkland, GL Sarlo, KF Holton - Nutrients, 2018 - mdpi.com
Magnesium is well known for its diverse actions within the human body. From a neurological
standpoint, magnesium plays an essential role in nerve transmission and neuromuscular …

Mercury involvement in neuronal damage and in neurodegenerative diseases

VL Cariccio, A Samà, P Bramanti, E Mazzon - Biological trace element …, 2019 - Springer
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and multiple sclerosis are characterized by a chronic and …

Free radicals in Alzheimer's disease: Lipid peroxidation biomarkers

C Peña-Bautista, M Baquero, M Vento… - Clinica Chimica …, 2019 - Elsevier
Abstract Alzheimer's disease (AD), the most common form of dementia, has tremendous
social and economic impact worldwide. Research has shown an association between …

Consequences of disturbing manganese homeostasis

J Baj, W Flieger, A Barbachowska, B Kowalska… - International Journal of …, 2023 - mdpi.com
Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …

Metals in Alzheimer's disease

M Babić Leko, L Langer Horvat, E Španić Popovački… - Biomedicines, 2023 - mdpi.com
The role of metals in the pathogenesis of Alzheimer's disease (AD) is still debated. Although
previous research has linked changes in essential metal homeostasis and exposure to …

Oxidative stress and antioxidant defenses in mild cognitive impairment: A systematic review and meta-analysis

G Nantachai, A Vasupanrajit, C Tunvirachaisakul… - Ageing Research …, 2022 - Elsevier
This study aims to systematically review and meta-analyze the nitro-oxidative stress
(O&NS)/antioxidant (ANTIOX) ratio in the peripheral blood of people with mild cognitive …

New insights on the role of manganese in Alzheimer's disease and Parkinson's disease

AC Martins Jr, P Morcillo, OM Ijomone… - International journal of …, 2019 - mdpi.com
Manganese (Mn) is an essential trace element that is naturally found in the environment and
is necessary as a cofactor for many enzymes and is important in several physiological …

Revisiting the role of vitamins and minerals in Alzheimer's disease

H Shah, F Dehghani, M Ramezan, RB Gannaban… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common type of dementia that affects millions of
individuals worldwide. It is an irreversible neurodegenerative disorder that is characterized …

Quantitation of in vivo brain glutathione conformers in cingulate cortex among age‐matched control, MCI, and AD patients using MEGA‐PRESS

D Shukla, PK Mandal, M Tripathi… - Human brain …, 2020 - Wiley Online Library
Oxidative stress (OS) plays an important role in Alzheimer's disease (AD) and glutathione
(GSH) mitigates this effect by maintaining redox‐imbalance and free‐radical neutralization …

Early detection and prevention of Alzheimer's disease: role of oxidative markers and natural antioxidants

J Arslan, H Jamshed, H Qureshi - Frontiers in Aging Neuroscience, 2020 - frontiersin.org
Oxidative stress (OS) contributes to Alzheimer's disease (AD) pathology. OS can be a result
of increased reactive oxygen/nitrogen species, reduced antioxidants, oxidatively damaged …