Endothelial cells (ECs) that reside on the surface of blood vessels are constantly exposed to
mechanical stimulation, including shear stress. Fluid shear stress (FSS) controls multiple …

A striking feature of atherosclerosis is its highly non-uniform distribution within the arterial
tree. This has been attributed to variation in the haemodynamic wall shear stress (WSS) …

The blood-brain barrier (BBB) is a critical structure that serves as the gatekeeper between
the central nervous system and the rest of the body. It is the responsibility of the BBB to …

Biodegradable polymers are expected to be an alternative to plastics. Because of its high
biocompatibility, poly (lactic-co-glycolic acid)(PLGA) is widely used in medicine. It has been …

Extracellular vesicles (EVs) are increasingly used as delivery vehicles for drugs and
bioactive molecules, which usually require intravascular administration. The endothelial …

Targeted deletion of TRAF7 revealed that it is a crucial part of shear stress-responsive
MEKK3-MEK5-ERK5 signaling pathway induced in endothelial cells by blood flow. Similar to …

The photocatalytic membranes have been reported to treat textile dye effluents; however, it
is challenging to maintain their long-term functionality due to the poor binding stability of …

Fluid shear stress stimulates endothelial nitric oxide synthase (eNOS) activation and nitric
oxide (NO) production through multiple kinases, including protein kinase A (PKA), AMP …

The increasing cost of high-volume cultures and dependence on serum and growth factor
supplementation limit the affordability of mesenchymal stromal cell (MSC) therapies. This …

Endothelium health is essential to the regulation of physiological vascular functions.
Because of the critical capability of endothelial cells (ECs) to sense and transduce chemical …