With the completion of the human genome sequence, attention turned to identifying and
annotating its functional DNA elements. As a complement to genetic and comparative …

Abstract paml, currently in version 4, is a package of programs for phylogenetic analyses of
DNA and protein sequences using maximum likelihood (ML). The programs may be used to …

Genome size in mammals and birds shows remarkably little interspecific variation compared
with other taxa. However, genome sequencing has revealed that many mammal and bird …

The comparison of related genomes has emerged as a powerful lens for genome
interpretation. Here we report the sequencing and comparative analysis of 29 eutherian …

In phylogenetics, the unrooted model of phylogeny and the strict molecular clock model are
two extremes of a continuum. Despite their dominance in phylogenetic inference, it is …

We have conducted a comprehensive search for conserved elements in vertebrate
genomes, using genome-wide multiple alignments of five vertebrate species (human …

Abstract The University of California Santa Cruz (UCSC) Table Browser (http://genome.
ucsc. edu/cgi‐bin/hgText) provides text‐based access to a large collection of genome …

The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a
protein, but this does not mean that such RNAs do not contain information nor have function …

The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional
elements in the human genome sequence. The pilot phase of the Project is focused on a …

Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris),
together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The …